Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q3SKX1

Entry ID Method Resolution Chain Position Source
AF-Q3SKX1-F1 Predicted AlphaFoldDB

No variants for Q3SKX1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3SKX1

No associated diseases with Q3SKX1

6 regional properties for Q3SKX1

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 422 - 589 IPR000795
domain Small GTP-binding protein domain 425 - 581 IPR005225
domain Translation initiation factor IF-2, N-terminal 345 - 395 IPR006847
domain Initiation factor 2 associated domain, bacterial 60 - 98 IPR013575
domain Translation initiation factor IF- 2, domain 3 698 - 812 IPR023115
domain Translation initiation factor IF-2, domain II 597 - 691 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNVEQFAQEL KLPPQLLLEQ LKAAGVSKND VVDPVTEADK AHLLDYLRKM HGGGGGETGK
70 80 90 100 110 120
TKITITRKQT GEIRKTDSTG KSRTIQVEVR KSRTYVKRDP AALAAEALAA AEPAAAAPAA
130 140 150 160 170 180
PPPALEEVPA EPAPIEAQAP VAETPAAEPA VVEAPAPEPA VTAEVTAPAP VEAAPEPAPA
190 200 210 220 230 240
AKPEGEAAPV KKTTRIKKAS ILNEAEVKAR EDEARRHQAL LERQAADAKA RIEREALRKQ
250 260 270 280 290 300
AEAAREAAKL AEAQKAAAPA PAAPTEKTLH KPDKPAAAKG AKGPDKKPAG AWKDDAARRR
310 320 330 340 350 360
GGLKTRGGAA PDAGWRGRKG KSKSGQEETT FVAPTEPIVR EVLVPETITV AELAHKMSVK
370 380 390 400 410 420
AAEVIKALMK LGSMVTINQV LDQETAIIVV EEMGHIGKPA ALDTPEAFLI ETGEPGEAEM
430 440 450 460 470 480
VARPPVVTVM GHVDHGKTSL LDTIRRTRVA SGEAGGITQH IGAYHVETEK GVITFLDTPG
490 500 510 520 530 540
HEAFTAMRAR GAKATDIVVL VVAADDGVMP QTIEAIHHAK AAGVPLVVAV NKIDKPDANP
550 560 570 580 590 600
ERIRQELVAQ GVTPEEWGGD TQFVEVSAKA NTNINGLLDA ILLQAEVLEL QAPADGPAKG
610 620 630 640 650 660
IVIEARLDKG KGPVATLLVQ SGTLRRGDMV LAGQVYGRVR AMLDEAGKTV TEAGPSIPVE
670 680 690 700 710 720
IQGLSDVPQA GEDMMVLPDE RKAREIALFR QGKYRDVQLA KKQAAKLESM FDQMGQGEVQ
730 740 750 760 770 780
HLPIILKADM QGSYEGLAHA LGKISTDEVK VNIIHSGVGA ITESDVNLAL ASKAVLIGFN
790 800 810 820 830 840
VRADASARKL AESSGVDIRY YNIIYEAVDE VKAALSGMLA PEKKESVIGT VEVRQVFVIS
850 860 870 880 890 900
KVGTIAGCYV TDGVVKRGAG VRLIRNNVVI HQGELDSLKR FKDDVKEVKA NFECGLSLKN
910 920
FNDIQEGDIL EVFEVVEVAR SL