Q3MH14

PR
Gene name
fabZ
Protein name
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
Names
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase
Species
Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis)
KEGG Pathway
ava:Ava_0096
EC number
4.2.1.59: Hydro-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-53 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3MH14

Entry ID Method Resolution Chain Position Source
AF-Q3MH14-F1 Predicted AlphaFoldDB

No variants for Q3MH14

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3MH14

No associated diseases with Q3MH14

No regional properties for Q3MH14

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q3MH14

Functions

Description
EC Number 4.2.1.59 Hydro-lyases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity Catalysis of the reaction: (3R)-3-hydroxytetradecanoyl-
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity Catalysis of the reaction: (3R)-3-hydroxydecanoyl-
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-
3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-

2 GO annotations of biological process

Name Definition
fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
lipid A biosynthetic process The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKAPTSTEQP ATNEATTPPE IKTTFTSEEI QKLLPHRYPF LLVDKIIDYT PGKQAVGIKN
70 80 90 100 110 120
VTINEPHFTG HFPDRPLMPG VLIVEAMAQV GGIVMTQLPN LEGGLFVFAG IDKVRFRRQV
130 140 150 160
VPGDQLVMTV ELLWIKQRRF GKMQARAEVD GQLAAEGELM FSLIN