Q3M7Z9

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis)
KEGG Pathway
ava:Ava_3279
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

353-437 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3M7Z9

Entry ID Method Resolution Chain Position Source
AF-Q3M7Z9-F1 Predicted AlphaFoldDB

No variants for Q3M7Z9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3M7Z9

No associated diseases with Q3M7Z9

9 regional properties for Q3M7Z9

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 12 - 142 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 331 - 466 IPR001247-2
domain S1 domain 628 - 700 IPR003029
domain K Homology domain 562 - 627 IPR004087
domain K Homology domain, type 1 567 - 623 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 146 - 209 IPR015847-1
domain Exoribonuclease, phosphorolytic domain 2 470 - 539 IPR015847-2
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 240 - 328 IPR015848
domain RNA-binding domain, S1 630 - 700 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAEFEKSISF DGRDIRLKVG LLAPQAGGSV LIESGDTAVL VTATRSAGRE GIDFLPLTVD
70 80 90 100 110 120
YEERLYAAGR IPGGIMRREG RPPEKTILTS RLIDRPLRPL FPSWLRDDLQ IVALTMSMDE
130 140 150 160 170 180
QVPPDVLAVT GASIATLIAK IPFNGPMAAV RVGLVGDDFI INPTYAEIEA GDLDLVVAGS
190 200 210 220 230 240
PHGVIMVEAG ANQLPERDII EAIDFGYEAV RDLIKAQLDL VAELGLEIVQ EAPPEVDQTL
250 260 270 280 290 300
ENYIRDRASD EIKKILAQFE LTKPERDAAL DVVKDNIATA IAELPEEDPI RLAATANSKA
310 320 330 340 350 360
LGNTFKDITK YFMRRQIVED NVRVDGRKLD QVRPVSSQVG VLPKRVHGSG LFNRGLTQVL
370 380 390 400 410 420
SACTLGTPGD AQNLNDDLQT DQSKRYLHHY NFPPFSVGET KPLRAPGRRE IGHGALAERA
430 440 450 460 470 480
ILPVLPPKEQ FPYVIRVVSE VLSSNGSTSM GSVCGSTLAL MDAGVPILKP VSGAAMGLIK
490 500 510 520 530 540
EGDEVRVLTD IQGIEDFLGD MDFKVAGTDA GITALQMDMK ISGLSLEVIA QAIHQAKDAR
550 560 570 580 590 600
LHILDKMLQT IDTPRTETSP YAPRLLTIKI DPDMIGLVIG PGGKTIKGIT EETGAKIDIE
610 620 630 640 650 660
DDGTVTISAV DENKAKRARN IVQGMTRKLN EGDVYAGRVT RIIPIGAFVE FLPGKEGMIH
670 680 690 700 710
ISQLADYRVG KVEDEVAVGD EVIVKVREID NKGRINLTRL GIHPDQAAAA REAAAVNR