Q3KPP4

PR
Gene name
mogat1
Protein name
2-acylglycerol O-acyltransferase 1
Names
Acyl-CoA:monoacylglycerol acyltransferase 1, MGAT1, Monoacylglycerol O-acyltransferase 1
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:380391
EC number
2.3.1.22: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

157-227 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3KPP4

Entry ID Method Resolution Chain Position Source
AF-Q3KPP4-F1 Predicted AlphaFoldDB

No variants for Q3KPP4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3KPP4

No associated diseases with Q3KPP4

No regional properties for Q3KPP4

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q3KPP4

Functions

Description
EC Number 2.3.1.22 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
2-acylglycerol O-acyltransferase activity Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.

2 GO annotations of biological process

Name Definition
glycerol metabolic process The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
triglyceride biosynthetic process The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKVEFAPLNI PLARRLQTTA VFQWVFSFLL LAQCCIGIFI CLVLARVWLL LALYVLWLYL
70 80 90 100 110 120
DWETPQAGGR RWEWVRNWPV WKYFKDYFPI RLVKTCDLDP QHNYIMGFHP HGVLVAGAFG
130 140 150 160 170 180
NFCTNYTGFK ELFPGLTPYL HILPFWFRCP FFREYIMSVG LVSASKKSVN HVLSKEDGGN
190 200 210 220 230 240
VSIIVTGGAE ESLDAHPGSL TLNILKRKGF IKVALKRGAY LVPVFSFGEN ELFQQVSNPK
250 260 270 280 290 300
GSLLRCVQER LQRIMGLAMP LFHARGIFQY SFGLMPYRMP IHTVVGRPIP VKETSHPTQE
310 320 330
EIESLHQQYL GALQELFEEH KKRYGIPEHE SLIFI