Q3KKX2

PR
Gene name
gpmA
Protein name
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Names
BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM
Species
Chlamydia trachomatis serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13)
KEGG Pathway
cta:CTA_0784
EC number
5.4.2.11: Phosphotransferases (phosphomutases)
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

57-155 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3KKX2

Entry ID Method Resolution Chain Position Source
AF-Q3KKX2-F1 Predicted AlphaFoldDB

No variants for Q3KKX2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3KKX2

No associated diseases with Q3KKX2

1 regional properties for Q3KKX2

Type Name Position InterPro Accession
active_site Phosphoglycerate/bisphosphoglycerate mutase, active site 6 - 15 IPR001345

Functions

Description
EC Number 5.4.2.11 Phosphotransferases (phosphomutases)
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; this reaction requires the cofactor 2,3-bisphosphoglycerate.

2 GO annotations of biological process

Name Definition
gluconeogenesis The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
glycolytic process The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTLLILLRHG QSVWNQKNLF TGWVDIPLSQ QGIQEAIAAG ESIKHLPIDC IFTSTLVRSL
70 80 90 100 110 120
ITALLAMTNH SSQKVPYIVH EERPDMSRIH SQKEMEQMIP LFQSSALNER MYGELQGKNK
130 140 150 160 170 180
QEVAAQFGEE QVKLWRRSYR IAPPQGESLF DTGQRTLPYF QERIFPLLQQ GKNIFISAHG
190 200 210 220
NSLRSLIMDL EKLSEEQVLS LELPTGQPIV YEWTGQKFTK HAPSLG