Q3KJE6
Gene name |
hutH |
Protein name |
Histidine ammonia-lyase |
Names |
Histidase |
Species |
Pseudomonas fluorescens (strain Pf0-1) |
KEGG Pathway |
pfo:Pfl01_0366 |
EC number |
4.3.1.3: Ammonia-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3KJE6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3KJE6-F1 | Predicted | AlphaFoldDB |
No variants for Q3KJE6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q3KJE6 | |||||
No associated diseases with Q3KJE6
1 regional properties for Q3KJE6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| active_site | Phenylalanine/histidine ammonia-lyases, active site | 139 - 155 | IPR022313 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.3.1.3 | Ammonia-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| histidine ammonia-lyase activity | Catalysis of the reaction: L-histidine = urocanate + NH3. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| histidine catabolic process to glutamate and formamide | The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formamide. |
| histidine catabolic process to glutamate and formate | The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTALNLIPGQ | LSLAQLRDVY | QNPVKLTLDN | SASAQIEASV | ACVEQILAEN | RTAYGINTGF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GLLASTRIAS | EDLENLQRSL | VLSHAAGVGQ | PISDELVRLI | MVLKVNSLSR | GFSGIRRVVI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DALIALINAE | VYPHIPLKGS | VGASGDLAPL | AHMSLVLLGE | GKARHKGEWM | DATEALKVAG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LTPLTLAAKE | GLALLNGTQV | STAFALRGLF | EGEDLFAGAL | ALGGLTVEAV | LGSRSPFDAR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IHAARGQKGQ | IDAAAAYRDL | LGERSEVSDS | HQNCEKVQDP | YSLRCQPQVM | GACLTQFRQA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AEVLAIEANA | VSDNPLVFAA | EGDVISGGNF | HAEPVAMAAD | NMALAIAEIG | SLSERRISLM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| MDKHMSQLPP | FLVANGGVNS | GFMIAQVTAA | ALASENKALS | HPHSVDSLPT | SANQEDHVSM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| APAAGKRLWE | MAENTRGILA | VEWLAAVQGL | DLRNGLKTSA | KLEQARGILR | REVPFYEKDR |
| 490 | 500 | ||||
| FFAPDINAAT | ELLASRILTE | LVPAKLLPSL |