Q3KE48
Gene name |
macB2 |
Protein name |
Macrolide export ATP-binding/permease protein MacB 2 |
Names |
|
Species |
Pseudomonas fluorescens (strain Pf0-1) |
KEGG Pathway |
pfo:Pfl01_2215 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3KE48
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3KE48-F1 | Predicted | AlphaFoldDB |
No variants for Q3KE48
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q3KE48 | |||||
No associated diseases with Q3KE48
6 regional properties for Q3KE48
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 6 - 244 | IPR003439 |
| domain | AAA+ ATPase domain | 34 - 221 | IPR003593 |
| domain | ABC3 transporter permease protein domain | 530 - 644 | IPR003838 |
| conserved_site | ABC transporter-like, conserved site | 146 - 160 | IPR017871 |
| domain | MacB, ATP-binding domain | 6 - 222 | IPR017911 |
| domain | MacB-like periplasmic core domain | 275 - 494 | IPR025857 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| response to antibiotic | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSEPLLQLTG | ISRSFTAGDR | EFLALKNIDL | TIHAGEMVAI | IGASGSGKST | LMNILGCLDY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ATAGSYRING | RETRDLDNQA | LAELRRDYFG | FIFQRYHLLP | HLSAVHNVEM | PAIYAGTPEP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QRHARARELL | ARLGLEGHLT | HRPSQLSGGQ | QQRVSIARAL | MNGGEVILAD | EPTGALDTTS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GKEVMRILLE | LHAAGHTVIL | VTHDPKVAAN | AERIIEVSDG | EILSDRRNER | DTAALSNEDA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VPKSTAARRL | VASLGLFKEA | FNMAWVALIS | HRMRTLLTML | GIVIGITSVV | SISAIGEGAK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RYVLKDIQAI | GSNTIDIYSG | TSFGDSRSAA | IETLVPADVT | ALNQLYYVDS | ATPVVGRNLL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LRYRNIDLDA | QVNGVSDLYF | QVRGIKMESG | IPFSESDARR | QAQVVVIDHN | TRHRLFGEGV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DPLGQVILIG | NLPCTVIGVA | AENKNIFSSS | KSLNVWVPYE | TAAGRLLGQR | YLDSISVRIK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DGQPSKVVED | NVNKLMLQRH | GTKDFFTNNL | DSVMQTVQKT | SRSLALLLSL | IAVISLVVGG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IGVMNIMLVS | VTERTREIGI | RMAVGARQSD | IRQQFLVEAV | MVCLLGGAIG | ISLSYAIGHL |
| 610 | 620 | 630 | 640 | 650 | |
| FSLFIKEWEM | VFSLTSVLTA | VICSTLIGIV | FGFVPARNAS | RLDPIEALAR | D |