Q3J7E7
Gene name |
mdh |
Protein name |
Malate dehydrogenase |
Names |
|
Species |
Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107) |
KEGG Pathway |
noc:Noc_2802 |
EC number |
1.1.1.37: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3J7E7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3J7E7-F1 | Predicted | AlphaFoldDB |
No variants for Q3J7E7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q3J7E7 | |||||
No associated diseases with Q3J7E7
Functions
| Description | ||
|---|---|---|
| EC Number | 1.1.1.37 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| L-malate dehydrogenase activity | Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| carboxylic acid metabolic process | The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). |
| tricarboxylic acid cycle | A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAIKKITIVG | AGRVGEATAQ | FLVKNELCRE | LVLLDAQEGV | AQGAALDIQQ | SAPLFDFDAR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VTGSTNYELI | ADSDLVVITA | GKPRKPGMSR | SDVLDSNLPI | ITDIMNNVMR | FAPQSLVMIV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TNPVDVLTYH | AWRHCGWDRA | RVFGQAGVLD | SARMASFIAG | ETGLSVKDIS | AMVLGGHGDT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MLPLIRYTTI | SGIPLTHFLD | QQVIEKIIER | TRHGGFEILR | LRQTSSAYDA | PAAAIAGMVD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AIRHNRKRIL | PCVAILQGEY | GENEVAMGVP | SVLGGDGLER | IVELPLTEEE | QEQFKHSVEA |
| 310 | |||||
| IRTDLAHLAR | A |