Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q3J6U6

Entry ID Method Resolution Chain Position Source
AF-Q3J6U6-F1 Predicted AlphaFoldDB

No variants for Q3J6U6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3J6U6

No associated diseases with Q3J6U6

1 regional properties for Q3J6U6

Type Name Position InterPro Accession
domain Uroporphyrinogen decarboxylase (URO-D) 2 - 333 IPR000257

Functions

Description
EC Number 4.1.1.37 Carboxy-lyases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
uroporphyrinogen decarboxylase activity Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2.

1 GO annotations of biological process

Name Definition
protoporphyrinogen IX biosynthetic process The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAELKNDRFL RALLRQPVDR TPIWIMRQAG RYLPEYREVR AKAGDFLTLC TTPELACEVT
70 80 90 100 110 120
LQPLRRFDLD AAIIFSDILT IPHAMGLGLY FSKGEGPRFE RPVRTKNQVS ALGVPDPESD
130 140 150 160 170 180
LSYVMEALRL TRRELDGRVP LIGFSGSPWT LACYMVEGGS SKDFALIKGL MFEHPQVMHH
190 200 210 220 230 240
LLEILAQAVT VYLNAQIAAG AQAVMLFDTW GGALSHRDYR DFSLSYMARI VEGVVRENEG
250 260 270 280 290 300
RQVPVILFTK GGGLWLETMA GTGCDALGVD WTVDLAKARM QVGKQVALQG NMDPCVLYAS
310 320 330 340 350
SERVRQEASE IIKAYGAGSG HVFNLGHGIH PTVMPEKVAA LVDAVHELSV PYHTYEE