Q3J5C7

PR
Gene name
glyS
Protein name
Glycine--tRNA ligase beta subunit
Names
Glycyl-tRNA synthetase beta subunit, GlyRS
Species
Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter sphaeroides)
KEGG Pathway
rsp:RSP_1858
EC number
6.1.1.14: Ligases forming aminoacyl-tRNA and related compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

33-103 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3J5C7

Entry ID Method Resolution Chain Position Source
AF-Q3J5C7-F1 Predicted AlphaFoldDB

No variants for Q3J5C7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3J5C7

No associated diseases with Q3J5C7

3 regional properties for Q3J5C7

Type Name Position InterPro Accession
domain Anticodon-binding 475 - 565 IPR004154
domain Aminoacyl-tRNA synthetase, class II 4 - 468 IPR006195
domain Glycyl-tRNA synthetase-like core domain 9 - 341 IPR033731

Functions

Description
EC Number 6.1.1.14 Ligases forming aminoacyl-tRNA and related compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
arginine-tRNA ligase activity Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
glycine-tRNA ligase activity Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).

2 GO annotations of biological process

Name Definition
arginyl-tRNA aminoacylation The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
glycyl-tRNA aminoacylation The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPDLLIELFS EEIPARMQAR AREDLKKLVT DGLVEAGLTY ASAGAFSTPR RLVLSVEGLS
70 80 90 100 110 120
AESPTLREER KGPKADAPAA AIEGFLRSTG LTRDQLETRE DKKGAVLFAV VEKPGRPAPE
130 140 150 160 170 180
IVAEVLERTI RTFPWPKSMR WGTGSLRWVR PLQSILCLLS DEAGAEVVPM TLDGLTAGNS
190 200 210 220 230 240
TEGHRFMAPA RFAVSGFEDY RAKLARAFVM LDASEREQAI WHEATTQAFA QGLEVVPDAA
250 260 270 280 290 300
LLSEVAGLVE WPVVLMGAIG EDFLGLPPEV LQTSMREHQK FFSVTNPATG RIEKFVTVAN
310 320 330 340 350 360
RETADHGETI LKGNGKVLSA RLSDARFFWE NDLRTVKTAG LEGMAEGLKQ VTFHNRLGSQ
370 380 390 400 410 420
AARIARIEAL AREIAPLVGA SPDLAAEAAR VAKADLQSAM VGEFPELQGT MGSYYARAAG
430 440 450 460 470 480
LPEAVAQACK AHYQPLGPSD AVPTDPVSVA VALADKIDTL AGFWRIGEKP TGSKDPFALR
490 500 510 520 530 540
RAALGVIRLL LTNNSRAGLM GIMLPAMNRH LEPFDTSDFT PYERDLLAFF HDRLKVHLRE
550 560 570 580 590 600
QGIRHDVIDA CLAMPGNDDL TLLVKRAEAL SAFLKTDDGT NLLQGFKRAN NILTQAEAKD
610 620 630 640 650 660
GVEYSFGADP KFAETDAERA LFAALETAEA AIGPALQAED FAAAMSAMAA LRAPIDAFFE
670 680 690
TVQVNADNAV LRRNRLNMLH SIRATCARVA DLTRIEG