Q3IME2
Gene name |
argG |
Protein name |
Argininosuccinate synthase |
Names |
Citrulline--aspartate ligase |
Species |
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis) |
KEGG Pathway |
nph:NP_5252A |
EC number |
6.3.4.5: Other carbon--nitrogen ligases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3IME2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3IME2-F1 | Predicted | AlphaFoldDB |
No variants for Q3IME2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q3IME2 | |||||
No associated diseases with Q3IME2
2 regional properties for Q3IME2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Argininosuccinate synthase, conserved site | 10 - 18 | IPR018223-1 |
| conserved_site | Argininosuccinate synthase, conserved site | 117 - 128 | IPR018223-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 6.3.4.5 | Other carbon--nitrogen ligases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| argininosuccinate synthase activity | Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| arginine biosynthetic process | The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSDKNRVALA | FSGGLDTTVC | VPLLEEEYGY | DEVIGVTVDV | GQPEAEFKEA | EETAEALDLE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HHVVDAKPEF | AELCFDAVRA | NASYQGYPLG | TALARPVIAE | AILEVAKEEG | CSGVAHGSTG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KGNDQLRFEA | VWRDSDLEVI | APVRELGLTR | TFEQEYAEER | GLPIEGGDEG | KYSIDTNLWS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RSIEGSELEE | PGYVPPEDIY | EWTTAPTAET | LEVEVGFEDG | YPVSLDGEKL | EPVELIETLN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DLAGDYGVGR | TDIMEDRMLG | LKVRENYEHP | AATVLLNAHQ | ALEDLVLTKE | ERAFKKQVDH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EWSEKGYQGL | VNAPLVDALE | GFIDETQDRV | TGTVTIRFEG | GQARPVGRES | PYAVYSAEAA |
| 370 | 380 | 390 | |||
| SFNTEDVTGG | IEQSDATGVA | KYHGFQERLA | NRVIDAADEE |