Q3IJQ0

PR
Gene name
cyoE2
Protein name
Protoheme IX farnesyltransferase 2
Names
Heme B farnesyltransferase 2, Heme O synthase 2
Species
Pseudoalteromonas translucida (strain TAC 125)
KEGG Pathway
pha:PSHAa2865
EC number
2.5.1.141: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-129 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3IJQ0

Entry ID Method Resolution Chain Position Source
AF-Q3IJQ0-F1 Predicted AlphaFoldDB

No variants for Q3IJQ0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3IJQ0

No associated diseases with Q3IJQ0

1 regional properties for Q3IJQ0

Type Name Position InterPro Accession
domain Phosphoadenosine phosphosulphate reductase 29 - 257 IPR002500

Functions

Description
EC Number 2.5.1.141 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
protoheme IX farnesyltransferase activity Catalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme O + diphosphate.

1 GO annotations of biological process

Name Definition
heme O biosynthetic process The chemical reactions and pathways resulting in the formation of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MALTIDKKAI QPINTLPLIT RSYNLLQDYL AISKFKVVAM LVLTAWVGLA LAPDVGRGMG
70 80 90 100 110 120
VQFISLLGIG LLSAAAAVIN HVVDSEIDSK MARTRHRPVA KGRLSKAHAL SFAAIIGVAG
130 140 150 160 170 180
FIMLMLWANT LTAILTLFAL VGYAFVYTSF LKRATPQNIV IGGLAGAMPP LLGWVSETGQ
190 200 210 220 230 240
MAAAPWLLVM IIFTWTPPHF WALAIARKSD YARAKIPMLP VTHGIDFSKT CVVAYSVLLA
250 260 270 280 290 300
IVCIFPYLIG MSGLIYLIGA SGLNAVFIYK AIKLKLAAND DTAMDLFRFS IIHLMVLFII
LFIDKWLLL