Q3IGZ3

PR
Gene name
rlmL
Protein name
Ribosomal RNA large subunit methyltransferase K/L
Names
Species
Pseudoalteromonas translucida (strain TAC 125)
KEGG Pathway
pha:PSHAa1667
EC number
2.1.1.173: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

353-428 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3IGZ3

Entry ID Method Resolution Chain Position Source
AF-Q3IGZ3-F1 Predicted AlphaFoldDB

No variants for Q3IGZ3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3IGZ3

No associated diseases with Q3IGZ3

3 regional properties for Q3IGZ3

Type Name Position InterPro Accession
domain Ribosomal RNA large subunit methyltransferase K/L-like, FLD domain 162 - 368 IPR000241
domain THUMP domain 32 - 154 IPR004114
domain S-adenosylmethionine-dependent methyltransferase 492 - 661 IPR019614

Functions

Description
EC Number 2.1.1.173 Methyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
23S rRNA (guanine(2445)-N(2))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine.
RNA binding Binding to an RNA molecule or a portion thereof.
rRNA (guanine-N7-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQFIALTSIG IENLLVDELT ELGATVSKQT VGSVRFEADS LLAQKVCLST RFATRVLMLI
70 80 90 100 110 120
EEKEGVDDKN SLYNFARSQP WQEWFGPTQT FAVDFNGTND SLKNTQFSGL VIKDAIVDYF
130 140 150 160 170 180
NDLFEQRPNV DKQDANVRVV ARLNRYGVSM YIDYSGPRLS ERGYRQGQGK APIKEHLAAA
190 200 210 220 230 240
LIKRSGWLEN VNQPLFDPCC GAGTILIEAA GMARNEAPGL FREGFAFERL PSFRAAKFKE
250 260 270 280 290 300
LKEELLGNII DPKLWLIGHD YDAQVLGKAI DNAKRAELDD IIKFKQSDAT KLTAVAKLPG
310 320 330 340 350 360
VVISNLPYGE RIGSMAELVD LHRNLGVGFK KHFNHWKLAL LGMDESLFKL LKLVRLKRYK
370 380 390 400 410 420
FKNGPLDVEL NLYQLDDKQV SLTTDDKKAL NFEGSMSFAN RLKKNKQGLK NWLKQNEITA
430 440 450 460 470 480
YRVYEADIPE YNVAVDIYGD SAVIFEYAAP KEIDEKTSEK RLQDVISLTA EQLKIAPENI
490 500 510 520 530 540
AVKVRKKQKG EEQYTPMAKQ NRTMVVEEFG AKFKVNLFDY LDTGLFLDHR LMRRYIQENA
550 560 570 580 590 600
KDKRFLNLFA YTGTASVHAA LGGAKAITTV DLSKTYLKWG QDNFDLNNIS NTRYRFEQAD
610 620 630 640 650 660
CLKWLEHATA QYDLIFLDPP TFSNSKRMKD AFDVQSDHIK LLTWVKKILS PSGTLIFSNN
670 680 690 700
KRGFVMDEVG LIGLGLKAVN ISDKTLSPDF KRNKKIHNSW LITHG