Q3EBC2
Gene name |
PAT17 (At3g04970, T9J14.8) |
Protein name |
Probable protein S-acyltransferase 17 |
Names |
Probable palmitoyltransferase At3g04970, Zinc finger DHHC domain-containing protein At3g04970 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G04970 |
EC number |
2.3.1.225: Transferring groups other than amino-acyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3EBC2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3EBC2-F1 | Predicted | AlphaFoldDB |
32 variants for Q3EBC2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_1376271_G_T | 11 | G>V | No | 1000Genomes | |
| ENSVATH05772744 | 18 | V>F | No | 1000Genomes | |
| tmp_3_1376307_G_T | 23 | C>F | No | 1000Genomes | |
| ENSVATH05772745 | 28 | I>T | No | 1000Genomes | |
| tmp_3_1376716_A_C | 85 | I>L | No | 1000Genomes | |
| ENSVATH00306462 | 117 | F>C | No | 1000Genomes | |
| tmp_3_1376918_T_C | 121 | I>T | No | 1000Genomes | |
| ENSVATH05772750 | 149 | A>T | No | 1000Genomes | |
| ENSVATH10496105 | 168 | P>Q | No | 1000Genomes | |
| ENSVATH10496106 | 180 | N>D | No | 1000Genomes | |
| ENSVATH10496106 | 180 | N>H | No | 1000Genomes | |
| tmp_3_1377346_A_G | 202 | T>A | No | 1000Genomes | |
| tmp_3_1377360_G_T | 206 | M>I | No | 1000Genomes | |
| ENSVATH05772758 | 241 | T>A | No | 1000Genomes | |
| tmp_3_1377700_G_A | 246 | V>I | No | 1000Genomes | |
| tmp_3_1377718_A_C | 252 | S>R | No | 1000Genomes | |
| ENSVATH10496109 | 257 | V>L | No | 1000Genomes | |
| ENSVATH00306468 | 262 | V>I | No | 1000Genomes | |
| ENSVATH00306469 | 280 | L>F | No | 1000Genomes | |
| tmp_3_1377907_C_T | 283 | A>V | No | 1000Genomes | |
| ENSVATH00306470 | 286 | F>L | No | 1000Genomes | |
| tmp_3_1378109_G_C | 322 | A>P | No | 1000Genomes | |
| tmp_3_1378160_G_A | 339 | E>K | No | 1000Genomes | |
| ENSVATH10496111 | 342 | C>F | No | 1000Genomes | |
| ENSVATH13870879 | 344 | G>R | No | 1000Genomes | |
| ENSVATH05772767 | 351 | A>D | No | 1000Genomes | |
| ENSVATH05772766 | 351 | A>T | No | 1000Genomes | |
| ENSVATH05772768 | 359 | D>E | No | 1000Genomes | |
| tmp_3_1378220_G_T | 359 | D>Y | No | 1000Genomes | |
| ENSVATH05772769 | 360 | A>V | No | 1000Genomes | |
| ENSVATH10496112 | 376 | S>F | No | 1000Genomes | |
| tmp_3_1378335_A_G | 397 | E>G | No | 1000Genomes |
No associated diseases with Q3EBC2
1 regional properties for Q3EBC2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Palmitoyltransferase, DHHC domain | 157 - 305 | IPR001594 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.1.225 | Transferring groups other than amino-acyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasmic vesicle membrane | The lipid bilayer surrounding a cytoplasmic vesicle. |
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein-cysteine S-palmitoyltransferase activity | Catalysis of the transfer of a palmitoyl (systematic name, hexadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction hexadecanoyl-CoA + L-cysteinyl- |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| peptidyl-L-cysteine S-palmitoylation | The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine. |
| protein targeting to membrane | The process of directing proteins towards a membrane, usually using signals contained within the protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAVQWLLVCH | GMMTLTVVIS | FLCGQWPIFK | GTPFQWIHYF | LTFGAYDYFL | RFVGFVFGSK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GTDVILSVEY | FCCDRPNPIL | QVIYIAIMGS | TYFLTAKSSF | IYIPGYYLGD | VHKYTSFLAV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IVGVILFLLT | CFSDPGTVNA | ENVSRYISAY | PYDDIIYSKK | ECSTCKIPKP | ARSKHCSICN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RCVARFDHHC | GWMNNCIGER | NTKYFMAFLL | WHFLLCLYGT | VAIGFILAGR | VKELRVVHIL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TVYYGVDKSF | RSLAPRVIQW | LVGTYNTQIL | LMVFLAIVSL | LLAGFFAYHA | NLCLTNTTTN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ETFKWREYIS | LNKKLSEAKA | SAAALKAGMS | CELKKPSAES | KCFGLCGRSS | AREEEVKADA |
| 370 | 380 | 390 | |||
| IAKRNLYDRG | SFQNVSEIVF | PLSSRPSSSN | KSKRKSE |