Q3E9Z9
Gene name |
ALMT11 (At4g17585, FCAALL.48) |
Protein name |
Putative aluminum-activated malate transporter 11 |
Names |
AtALMT11 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G17585 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3E9Z9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3E9Z9-F1 | Predicted | AlphaFoldDB |
40 variants for Q3E9Z9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH11933486 | 2 | S>T | No | 1000Genomes | |
| tmp_4_9793244_G_A | 6 | H>Y | No | 1000Genomes | |
| ENSVATH11933485 | 12 | M>I | No | 1000Genomes | |
| ENSVATH06704921 | 21 | W>* | No | 1000Genomes | |
| tmp_4_9793192_A_G | 23 | V>A | No | 1000Genomes | |
| ENSVATH06704920 | 25 | E>K | No | 1000Genomes | |
| tmp_4_9793142_C_A | 40 | V>F | No | 1000Genomes | |
| ENSVATH06704919 | 43 | E>K | No | 1000Genomes | |
| ENSVATH06704917 | 48 | V>E | No | 1000Genomes | |
| ENSVATH06704917 | 48 | V>G | No | 1000Genomes | |
| ENSVATH06704918 | 48 | V>M | No | 1000Genomes | |
| ENSVATH02867140 | 52 | F>L | No | 1000Genomes | |
| ENSVATH02867139 | 53 | K>R | No | 1000Genomes | |
| ENSVATH11933453 | 54 | V>I | No | 1000Genomes | |
| ENSVATH02867138 | 56 | H>L | No | 1000Genomes | |
| ENSVATH14237934 | 59 | T>S | No | 1000Genomes | |
| ENSVATH11933452 | 62 | S>Y | No | 1000Genomes | |
| tmp_4_9793046_T_C | 72 | K>E | No | 1000Genomes | |
| ENSVATH11933451 | 75 | G>R | No | 1000Genomes | |
| tmp_4_9793018_G_T | 81 | A>D | No | 1000Genomes | |
| tmp_4_9793019_C_A | 81 | A>S | No | 1000Genomes | |
| ENSVATH00517054 | 82 | V>L | No | 1000Genomes | |
| ENSVATH00517053 | 87 | A>V | No | 1000Genomes | |
| ENSVATH02867135 | 89 | L>V | No | 1000Genomes | |
| ENSVATH09586162 | 90 | L>F | No | 1000Genomes | |
| ENSVATH06704915 | 94 | A>P | No | 1000Genomes | |
| ENSVATH06704914 | 95 | V>L | No | 1000Genomes | |
| ENSVATH06704914 | 95 | V>M | No | 1000Genomes | |
| tmp_4_9792678_C_T | 102 | E>K | No | 1000Genomes | |
| tmp_4_9792675_T_A | 103 | K>* | No | 1000Genomes | |
| ENSVATH06704906 | 114 | E>D | No | 1000Genomes | |
| tmp_4_9792633_C_G | 117 | A>P | No | 1000Genomes | |
| tmp_4_9792618_G_A | 122 | R>W | No | 1000Genomes | |
| ENSVATH00517046 | 125 | A>T | No | 1000Genomes | |
| ENSVATH00517044 | 136 | P>L | No | 1000Genomes | |
| ENSVATH11933333 | 137 | K>R | No | 1000Genomes | |
| tmp_4_9792552_G_T | 144 | Q>K | No | 1000Genomes | |
| ENSVATH02867128 | 147 | V>A | No | 1000Genomes | |
| ENSVATH02867129 | 147 | V>I | No | 1000Genomes | |
| tmp_4_9792522_GC_G | 153 | Y>del | No | 1000Genomes |
1 associated diseases with Q3E9Z9
[MIM: 613728]: Spinocerebellar ataxia, autosomal recessive, 10 (SCAR10)
A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAR10 is characterized by onset in the teenage or young adult years of gait and limb ataxia, dysarthria, and nystagmus associated with marked cerebellar atrophy on brain imaging. {ECO:0000269|PubMed:21092923}. Note=The disease is caused by variants affecting the gene represented in this entry.
Without disease ID
- A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAR10 is characterized by onset in the teenage or young adult years of gait and limb ataxia, dysarthria, and nystagmus associated with marked cerebellar atrophy on brain imaging. {ECO:0000269|PubMed:21092923}. Note=The disease is caused by variants affecting the gene represented in this entry.
No regional properties for Q3E9Z9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q3E9Z9 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plant-type vacuole membrane | The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| ion transmembrane transport | A process in which an ion is transported across a membrane. |
| malate transport | The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O23086 | ALMT10 | Aluminum-activated malate transporter 10 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSNKVHVGNI | EMEEGLSKTK | WMVLEPSEKI | KKIPKRLWSV | GKEDPRRVIH | AFKVGHSLTL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VSLLYFMENL | FKGIGSNAIW | AVMTVVAVLL | EFFAVEGLTI | SEKVILSMAA | RGRESAAEPH |
| 130 | 140 | 150 | |||
| ERNEAGNVCH | SIKFLPKSIA | RAKQHHVLNQ | PY |