Q3B7L1
Gene name |
Plekhh3 |
Protein name |
Pleckstrin homology domain-containing family H member 3 |
Names |
PH domain-containing family H member 3 |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:360634 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3B7L1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3B7L1-F1 | Predicted | AlphaFoldDB |
No variants for Q3B7L1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q3B7L1 | |||||
No associated diseases with Q3B7L1
6 regional properties for Q3B7L1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ras-associating domain | 402 - 496 | IPR000159 |
| domain | FERM domain | 404 - 755 | IPR000299 |
| domain | MyTH4 domain | 237 - 399 | IPR000857 |
| domain | Pleckstrin homology domain | 95 - 201 | IPR001849 |
| domain | FERM central domain | 510 - 660 | IPR019748 |
| domain | Band 4.1 domain | 400 - 662 | IPR019749 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoskeleton | A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| signal transduction | The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8VCE9 | Plekhh3 | Pleckstrin homology domain-containing family H member 3 | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPLPGGLWWL | LCCRRGFTLL | HRDYGDGELS | GDGDEDEDDE | TFELRSPSPA | GGGRGSLDVT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LTQPTRNGPI | TDRLQSWEET | WSLIPDKGLP | EDDPDVIVKG | WLYREPRGGG | ARPWLLPRRA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| WFVLTRDSLD | QFSSSGKGAR | RLGSLVLTSL | CSVTGPERRP | KETGLWSVTV | SGRKHSIRLC |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SPRQAEAERW | GVALREVIAS | KAPLETPTQL | LLRDIQESGG | DPEAVALIYR | RNPILRHTSS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ALYAPLLPLP | YEVSAPGPGY | APLREEAVRL | FLALQALEGA | RRPGPLMQGV | LQTCRDLPAL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QDELFLQLAK | QTSGPAGPPG | LPATQDPAAL | RYWQLLTCMS | CTFRPGGAVR | GHLLGHLERT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EQALPDSELA | EYARFIRKAL | GRTRGRELVP | SLAEISALSR | RQELLCTVHC | PGAGACPVSI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DSHTTAGEVA | RELVGRLGLA | RSRNAFALYE | QRGAQERALA | GGTLVADVLT | SLTSEEVGLE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DSPDSGWRLC | LRLHGPLHPE | GLSPEGHELP | FLFEQAHALL | LRGRPPPPDD | TLRALAALRL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| QSLHRDFSPR | GPLPLLDRLM | PPPAPPREQP | SRPARRPPPS | AALLAGALWS | PGLAKRRAER |
| 610 | 620 | 630 | 640 | 650 | 660 |
| ARRIGTGRST | ESTAQVGGGG | GGSTTAAVLG | GWKRLRGMGQ | AEAMAAYLAL | AAQCPGFGAA |
| 670 | 680 | 690 | 700 | 710 | 720 |
| RYDVLELSTE | PGGGAPQKLC | LGLGAKAMSL | SRPGESEPIH | SVSYGHVAAC | QLIGPHTLAL |
| 730 | 740 | 750 | 760 | 770 | 780 |
| RVGDSQLLLQ | SPQVEEIMEL | VNAYLANPSP | ERPCSSSGPP | SQDLSDTSPP | SQHQVLEKPQ |
| 790 | |||||
| GQSGCLRQLQ | D |