Q3ADA6

PR
Gene name
cheB2
Protein name
Protein-glutamate methylesterase/protein-glutamine glutaminase 2
Names
Species
Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)
KEGG Pathway
chy:CHY_1031
EC number
3.1.1.61: Carboxylic ester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

104-197 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3ADA6

Entry ID Method Resolution Chain Position Source
AF-Q3ADA6-F1 Predicted AlphaFoldDB

No variants for Q3ADA6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3ADA6

No associated diseases with Q3ADA6

2 regional properties for Q3ADA6

Type Name Position InterPro Accession
domain Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase 159 - 354 IPR000673
domain Signal transduction response regulator, receiver domain 4 - 122 IPR001789

Functions

Description
EC Number 3.1.1.61 Carboxylic ester hydrolases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
phosphorelay response regulator activity Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
protein-glutamate methylesterase activity Catalysis of the reaction: protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol.
protein-glutamine glutaminase activity Catalysis of the reaction: protein L-glutamine + H2O = protein L-glutamate + NH3.

3 GO annotations of biological process

Name Definition
chemotaxis The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
protein deamination The removal of an amino group from a protein amino acid.
protein demethylation The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKIRVLIVD DSALMRKYLR EILEQDPEIE VIAVARNGRE AVEKALELSP DVITMDINMP
70 80 90 100 110 120
EMDGLTAIQY IMLHRPTPII VISSLTQKGA LTTFEALELG AVDYVAKPDG TVSLKIKEVA
130 140 150 160 170 180
EEILQKVKAV AKSRGVVRLK ARKERPFVQE VPKTRPVSPD TSFKKLILIG VSTGGPKALM
190 200 210 220 230 240
EIIPRLPGNL DASVVIIQHM PEKFTASFAA RLNNYSELYV KEAEDGESLE RGKVLVARGG
250 260 270 280 290 300
INLKLERKLG INVVRVRYTP LPRETIYWPS VDVAFRSALT VIEPHRIIAV LLTGMGDDGA
310 320 330 340 350
QAMVEIKQKG GYTIAESEET AVVWGMPREA IERGGASEIL PVYQIADRIV ELVR