Q3ABA6

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)
KEGG Pathway
chy:CHY_1758
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

370-441 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3ABA6

Entry ID Method Resolution Chain Position Source
AF-Q3ABA6-F1 Predicted AlphaFoldDB

No variants for Q3ABA6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3ABA6

No associated diseases with Q3ABA6

9 regional properties for Q3ABA6

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 17 - 147 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 334 - 467 IPR001247-2
domain S1 domain 630 - 707 IPR003029
domain K Homology domain 563 - 628 IPR004087
domain K Homology domain, type 1 570 - 624 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 150 - 213 IPR015847-1
domain Exoribonuclease, phosphorolytic domain 2 470 - 539 IPR015847-2
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 248 - 331 IPR015848
domain RNA-binding domain, S1 631 - 707 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTTGRQILEK EIMIAGRPLK LTAGKVATQA SGSVLVSYGD TVVLVTATGS KEPREGIDFF
70 80 90 100 110 120
PLTVDYEERF YAVGKIPGGF IKREGRPSEK AILSARLIDR PIRPLFPKGF KNDVHIVATV
130 140 150 160 170 180
LSVNQDNPPE IAAMNGASAA LTLSHLPFLG PIGAVVVGLV EDELVINPTI EQAEKSRLHL
190 200 210 220 230 240
VVAGTRDAVM MVEAGAQEVP EEIMIEAITR GHEEVKKIVA FIEEFREEAL KLGLAKEKME
250 260 270 280 290 300
VVVEEKAELK EAVTAEAYPL LKEAIEKIIA EKFNKQERDE YLENLKKELT TKFLETYPEE
310 320 330 340 350 360
ELTIKGILDS IQKEIVRQKI LKEGIRIDGR KTDEVRPIWC EVGLLPRTHG SGLFTRGQTQ
370 380 390 400 410 420
VLSIVTLGAV GDVQILDDLG IEESKRFMHH YNFPPYSVGE VRPMRGPGRR EIGHGALAER
430 440 450 460 470 480
ALEPVIPPEE VFPYTIRIVS EVLESNGSTS MGSVCGSTLA LMDAGVPIKA PVAGVAMGLI
490 500 510 520 530 540
KEGDEVAILT DIQGIEDALG DMDFKVAGTK DGITALQMDI KIAGVTRDIL TKALAQAREG
550 560 570 580 590 600
RMHILGKMLE VISEPRKELS PYAPRIIFTT VDPEKIRDII GPGGKIIKKI IDETGVKIDI
610 620 630 640 650 660
EDDGRIFIAA VDKEAGEKAL NIIENLTKEI EVGKVYLGKV TRIADFGAFV EVVPGVLGLP
670 680 690 700 710 720
GKEGLVHISQ LAHSRVKRVE DVVKEGDQIL VKAIGYDNQG RLKLSRKDAI PAEEVREKKN
730
PPIHKPRREG K