Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q3AB98

Entry ID Method Resolution Chain Position Source
AF-Q3AB98-F1 Predicted AlphaFoldDB

No variants for Q3AB98

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3AB98

No associated diseases with Q3AB98

6 regional properties for Q3AB98

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 326 - 495 IPR000795
domain Small GTP-binding protein domain 331 - 485 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 53 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 249 - 300 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 601 - 716 IPR023115
domain Translation initiation factor IF-2, domain II 501 - 596 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRKKRVFEIA KELNMESKEV INRLKAIGVE VKSHMSTVEN HHLNLLLKAL NREKEEKEKK
70 80 90 100 110 120
EQEKKQVEQK AEAQKLQSHP QRPKEQQQSK QGGQSRPREQ RSDRPQGQRY AGNQRPEPRD
130 140 150 160 170 180
KDKGRRPGEQ RSFNQNRPRD DRRRFDKERG VQGPKPFGEK KERPPFPREK KKGVLPAIPK
190 200 210 220 230 240
PEAPKGENKE PERRKGAPDK KREWEKALKK EEKVFALEEK KLNLKKEKKQ EKQEKQEPVA
250 260 270 280 290 300
AEPKAIVIPE RMTVQEFAKI MGKSAAEVIK KLMSYGILAT INQEIDADTA TIIATDFGYE
310 320 330 340 350 360
VTVEKEEKED IWLLEETPDD PESLEPRPPI VTVMGHVDHG KTSLLDAIRQ TNVTATEAGG
370 380 390 400 410 420
ITQHIGAYQV EHNGRKITFI DTPGHEAFTA MRARGAQVTD IAILVVAADD GVMPQTVEAI
430 440 450 460 470 480
NHAKAAGVPI IVAVNKIDKP NAQPDRVKQQ LTEYGLIPEA WGGDTVFVEV SALKKIGIEE
490 500 510 520 530 540
LLEMILLVAD LKELKANPNK PARGTVIEAK LDKGRGPVAT VLVQSGTLNV GDVVVVGLTY
550 560 570 580 590 600
GRVRALMDDK GRRVKKATPS MPVEVLGLND VPSAGDILVV VDDEKTARTL AEKRQEQKRE
610 620 630 640 650 660
EELRASSKVS LEDLFKHIQE GKIKELNIVL KADVHGSVEA IKQSLSRLST EEVKVNVIHS
670 680 690 700 710 720
GVGAITETDI MLASASNAIV IGFNVRPDSN ARKLAETEKI DVRVYRIIYE LLDDIKAAMA
730 740 750 760 770 780
GLLEPEQKEV VLGRAEVRKT FKASKVGTIA GLYVLEGKIT RSAKVRVIRD GIVIHEGNVE
790 800 810 820
SLKRFKDDVR EVAQGYECGL TIEKFNDIRE GDIIEAFTIE EVKRTLE