Q3A825

PR
Gene name
nuoBCD (nuoB, nuoC, nuoD, Pcar_0206)
Protein name
NADH-quinone oxidoreductase subunit B/C/D
Names
NADH dehydrogenase I subunit B/C/D, NDH-1 subunit B/C/D
Species
Syntrophotalea carbinolica (strain DSM 2380 / NBRC 103641 / GraBd1) (Pelobacter carbinolicus)
KEGG Pathway
pca:Pcar_0206
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

147-247 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3A825

Entry ID Method Resolution Chain Position Source
AF-Q3A825-F1 Predicted AlphaFoldDB

No variants for Q3A825

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3A825

No associated diseases with Q3A825

3 regional properties for Q3A825

Type Name Position InterPro Accession
domain NADH-quinone oxidoreductase, subunit D 328 - 598 IPR001135
domain NADH:ubiquinone oxidoreductase, 30kDa subunit 49 - 176 IPR001268
conserved_site NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site 251 - 262 IPR014029

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

5 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
iron ion binding Binding to an iron (Fe) ion.
NAD binding Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
NADH dehydrogenase (ubiquinone) activity Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out).
quinone binding Binding to a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSESIPKNII LTTLDDAINW GRKNSMWPMF FGLSCCFVEM MGSMTPRFDL ARFGAEVLRG
70 80 90 100 110 120
TPREADLMVI AGTPFKKMAA SMLRVYEEMA NPKWVIAMGS CANSGGMYDV YSVMQGVNQV
130 140 150 160 170 180
LPVDVYIPGC PPRPEAFMQG LMTLQEKIAR KESPARPVLN LRGGNEGTTV PILIDGSSKT
190 200 210 220 230 240
RDTRGPGYGH CPIRGTAQQH PDFKGHRAAG MWGPPQPKIA FSASTAPLLE QLRERFGDDV
250 260 270 280 290 300
RQEEGADMPT LVADPAQVPE LLRFLKQDID QPYERLEDLT AIDETARSQR PAHDLTMVYH
310 320 330 340 350 360
LLSFERAGYL RVKAPLRNDR AEVPSITGLW PAANWYEREA FDMFGVRFAG HPDLRRILMP
370 380 390 400 410 420
EGWQGHPLRK SHPSRATDMP PFTRDTATTM VPPEGSHFFS NRAPVDNQSL SILNLGPQHP
430 440 450 460 470 480
GTHGILRVIL QLAGEEIVDL DSEIGYHHRG AEKIAERQHW NQYIPYTDRI DYLAGSLNNL
490 500 510 520 530 540
AYLYSVETLC GVEVPPRARY IRVLLSELFR IASHLVWLGT FAHDVGAMTP VFYAFDSREK
550 560 570 580 590 600
IFDIIELITG GRMHPAWFRI GGVPDDLPDG WLAAVEAFTR DFEARIDEFD RLLTGGPIFR
610 620 630 640 650 660
ARTEGIGTVS RQQAVELGFS GPNLRATGLA WDLRKSMPYG GYDEFDFDVV TAGGGDCFAR
670 680 690 700 710 720
YLVRLGELRQ SLRIVRQAAE GMPQGRWISD QYRYAYPKRE DGLQDIESLI HHFLHVSRGP
730 740 750 760 770 780
AAPRGECYRA IESSKGECGY YAVSDGGTGA YRLRIRTPSF PHLQALPQLS RGRLVADVIT
790
ILGSLDYVLA DLDR