Q3A526

PR
Gene name
hldE
Protein name
Bifunctional protein HldE
Names
Species
Syntrophotalea carbinolica (strain DSM 2380 / NBRC 103641 / GraBd1) (Pelobacter carbinolicus)
KEGG Pathway
pca:Pcar_1282
EC number
2.7.1.167: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

10-80 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3A526

Entry ID Method Resolution Chain Position Source
AF-Q3A526-F1 Predicted AlphaFoldDB

No variants for Q3A526

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3A526

No associated diseases with Q3A526

2 regional properties for Q3A526

Type Name Position InterPro Accession
domain Homogentisate 1,2-dioxygenase, C-terminal domain 275 - 427 IPR046451
domain Homogentisate 1,2-dioxygenase, N-terminal domain 9 - 274 IPR046452

Functions

Description
EC Number 2.7.1.167 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
heptose 7-phosphate kinase activity Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP.
heptose-1-phosphate adenylyltransferase activity Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose.
phosphotransferase activity, alcohol group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).

1 GO annotations of biological process

Name Definition
ADP-L-glycero-beta-D-manno-heptose biosynthetic process The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDRTNIENFL SRLKDLRALV IGDLMLDEYL WGRTERISPE APVQVVDVVR EDLRLGGAGN
70 80 90 100 110 120
VINNLVTLGC QVHVASVLGE GHDGLLLRRR LEEKQVGIEG LQFDAKRTTS RKTRILASGQ
130 140 150 160 170 180
QMMRFDRESR CPIDATQEAV LAEFVSNSAD RFDVILVSDY LKGVLTEDLL QSVIAVGKQK
190 200 210 220 230 240
GIPVVIDPKG NDYAKYRGAT LLTPNRKETE VASGISIVDE ESLRLAARTL MQRIDLETLM
250 260 270 280 290 300
VTRSEEGISI FFRNGEEVHL PTQAREVYDV TGAGDTVLSL VGLGLAGGLP VSEAAALANI
310 320 330 340 350 360
GAGIVVGKVG TSTVNVEELH EAMAHHALEY DSKIRLRESL RDVLEVERRR GKTVVFTNGC
370 380 390 400 410 420
FDLLHVGHVK YLQKARRLGD LLVLGLNSDA SIRRLKGPSR PLISEQERAH ILAALSCIDY
430 440 450 460 470 480
VVVFDEDTPL ELIDTLRPDI LVKGGDYTPE TVVGKDLVES YGGRVELIDL VDGRSTTNII
ERILDRYEQG