Q39KA4

PR
Gene name
thiG
Protein name
Thiazole synthase
Names
Species
Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)
KEGG Pathway
bur:Bcep18194_A3510
EC number
2.8.1.10: Sulfurtransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

218-271 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q39KA4

Entry ID Method Resolution Chain Position Source
AF-Q39KA4-F1 Predicted AlphaFoldDB

No variants for Q39KA4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q39KA4

No associated diseases with Q39KA4

1 regional properties for Q39KA4

Type Name Position InterPro Accession
domain Thiazole synthase ThiG 12 - 257 IPR033983

Functions

Description
EC Number 2.8.1.10 Sulfurtransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
thiazole synthase activity Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate- = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

1 GO annotations of biological process

Name Definition
thiamine diphosphate biosynthetic process +The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTSLTSADAL TLYGETFASR VLIGTSRYPS LQSLSDSIAA SRPGMVTVAL RRQMTGGTAE
70 80 90 100 110 120
AGFFDLLKRH AVPLLPNTAG CQTVAEAVTT AHMAREVFGT DWIKLELIGD DYTLQPDPVG
130 140 150 160 170 180
LIEAAAQLVK DGFKVLPYCT EDLVIGRRLL DVGCEALMPW GAPIGTGKGV VNPYGLRVLR
190 200 210 220 230 240
ERLPDVPLIV DAGLGVPSHA CQVMEWGFDG VLLNTAVSQA THPEIMARAF AQGVEAGRAA
250 260 270
YLAGPMDARE TAHASTPVVG MPFWHQDGGG A