Q39173
Gene name |
P2 (At5g16990, F2K13_140) |
Protein name |
NADP-dependent alkenal double bond reductase P2 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G16990 |
EC number |
1.3.1.74: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q39173
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q39173-F1 | Predicted | AlphaFoldDB |
44 variants for Q39173
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_5583835_C_A | 5 | K>N | No | 1000Genomes | |
| ENSVATH03065646 | 12 | H>Y | No | 1000Genomes | |
| tmp_5_5583813_C_T | 13 | V>M | No | 1000Genomes | |
| ENSVATH03065645 | 30 | E>D | No | 1000Genomes | |
| tmp_5_5583753_C_T | 33 | V>I | No | 1000Genomes | |
| tmp_5_5583706_TGACAGG_T | 46 | Y>* | No | 1000Genomes | |
| tmp_5_5583680_A_G | 57 | M>T | No | 1000Genomes | |
| ENSVATH10795140 | 66 | L>H | No | 1000Genomes | |
| ENSVATH10795139 | 69 | A>S | No | 1000Genomes | |
| tmp_5_5583636_G_A | 72 | P>S | No | 1000Genomes | |
| ENSVATH03065630 | 86 | E>D | No | 1000Genomes | |
| ENSVATH03065629 | 87 | S>T | No | 1000Genomes | |
| tmp_5_5583205_G_A | 90 | P>L | No | 1000Genomes | |
| ENSVATH06979287 | 95 | G>C | No | 1000Genomes | |
| ENSVATH06979286 | 95 | G>D | No | 1000Genomes | |
| tmp_5_5583183_T_A | 97 | L>F | No | 1000Genomes | |
| tmp_5_5583166_C_G | 103 | G>A | No | 1000Genomes | |
| ENSVATH00626339 | 114 | A>T | No | 1000Genomes | |
| tmp_5_5583131_G_T,A | 115 | H>N | No | 1000Genomes | |
| tmp_5_5583131_G_T,A | 115 | H>Y | No | 1000Genomes | |
| ENSVATH10795124 | 116 | M>I | No | 1000Genomes | |
| tmp_5_5583127_A_G | 116 | M>T | No | 1000Genomes | |
| tmp_5_5583128_T_C | 116 | M>V | No | 1000Genomes | |
| ENSVATH10795122 | 119 | K>* | No | 1000Genomes | |
| tmp_5_5583110_G_T | 122 | H>N | No | 1000Genomes | |
| ENSVATH06979285 | 122 | H>R | No | 1000Genomes | |
| tmp_5_5583101_C_A | 125 | V>F | No | 1000Genomes | |
| ENSVATH03065621 | 210 | S>P | No | 1000Genomes | |
| ENSVATH03065621 | 210 | S>T | No | 1000Genomes | |
| ENSVATH10795094 | 215 | A>V | No | 1000Genomes | |
| ENSVATH10795092 | 228 | F>Y | No | 1000Genomes | |
| ENSVATH06979269 | 240 | L>P | No | 1000Genomes | |
| tmp_5_5582135_A_G | 243 | M>T | No | 1000Genomes | |
| tmp_5_5582112_C_T | 251 | V>I | No | 1000Genomes | |
| ENSVATH06979267 | 258 | Y>N | No | 1000Genomes | |
| ENSVATH10795087 | 278 | R>C | No | 1000Genomes | |
| ENSVATH03065615 | 285 | A>S | No | 1000Genomes | |
| tmp_5_5581994_T_A | 290 | K>I | No | 1000Genomes | |
| ENSVATH06979266 | 292 | P>S | No | 1000Genomes | |
| tmp_5_5581961_C_T | 301 | R>H | No | 1000Genomes | |
| ENSVATH06979265 | 308 | T>A | No | 1000Genomes | |
| ENSVATH10795085 | 327 | L>I | No | 1000Genomes | |
| tmp_5_5581881_A_T | 328 | F>I | No | 1000Genomes | |
| ENSVATH08413506 | 340 | I>S | No | 1000Genomes |
No associated diseases with Q39173
Functions
| Description | ||
|---|---|---|
| EC Number | 1.3.1.74 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| plastid | Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2-alkenal reductase [NAD(P)+] activity | Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| response to oxidative stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTTNKQVIFK | DHVSGFPKES | DFNFTTTTVE | LRVPEGSKSV | LVKNLYLSCD | PYMRSRMGKP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DPSSALAQAY | APGKPIYGYG | VSRVIESGHP | DYKKGDLLWG | IVGWEEYSVI | TPMAHMHFKI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QHTDVPLSYY | TGLLGMPGMT | AYAGFYEVCS | PKKGETVYVS | AASGAVGQLV | GQFAKMMGCY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VVGSAGSKEK | VDLLKTKFGF | DDAFNYKEES | DLSAALKRCF | PKGIDMYFEN | VGGKMLDAVL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LNMNPHGRIA | VCGMISQYNL | ENQEGVHNLS | NIIYKRIRIQ | GFVVADFYDK | YPKFLELVLP |
| 310 | 320 | 330 | 340 | ||
| RIKEGKITYV | EDVADGLEKA | PEALVGLFHG | KNVGKQVVVI | ARE |