Q38IC8
Gene name |
IL2RA |
Protein name |
Interleukin-2 receptor subunit alpha |
Names |
|
Species |
Pan troglodytes (Chimpanzee) |
KEGG Pathway |
ptr:450884 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q38IC8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q38IC8-F1 | Predicted | AlphaFoldDB |
No variants for Q38IC8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q38IC8 | |||||
No associated diseases with Q38IC8
2 regional properties for Q38IC8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Sushi/SCR/CCP domain | 24 - 82 | IPR000436-1 |
| domain | Sushi/SCR/CCP domain | 123 - 186 | IPR000436-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| interleukin-2 binding | Binding to interleukin-2. |
| interleukin-2 receptor activity | Combining with interleukin-2 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| immune system process | Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. |
| inflammatory response | The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P01589 | IL2RA | Interleukin-2 receptor subunit alpha | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDSYLLMWGL | LTLIMVPGCF | AELCDDDPPE | ITHATFKAMA | YKEGTMLNCE | CKRGFRRIKS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GSLYMLCTGN | SSHSSWDNQC | QCTSSATRNT | TKQVTPQPEE | QKERKTTEMQ | SPMQPVDQAS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LPGHCREPPP | WENEATERIY | HFVVGQTVYY | QCVQGYRALH | RGPAESVCKM | THGKTRWTQP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QLICTGEMET | SQFPGEEKPQ | ASPEGRPESE | TSCLITTTDF | QIQTEMAATM | ETFIFTTEYQ |
| 250 | 260 | ||||
| VAVAGCVFLL | ISVLLLSGLT | WQRRQ |