Q32LH4

PR
Gene name
NIT1
Protein name
Deaminated glutathione amidase
Names
dGSH amidase, Nitrilase homolog 1
Species
Bos taurus (Bovine)
KEGG Pathway
bta:504199
EC number
3.5.1.128: In linear amides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-77 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q32LH4

Entry ID Method Resolution Chain Position Source
AF-Q32LH4-F1 Predicted AlphaFoldDB

No variants for Q32LH4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q32LH4

No associated diseases with Q32LH4

3 regional properties for Q32LH4

Type Name Position InterPro Accession
conserved_site Uncharacterised protein family UPF0012, conserved site 200 - 220 IPR001110
domain Carbon-nitrogen hydrolase 47 - 307 IPR003010
domain Nit1/2, carbon-nitrogen hydrolase domain 49 - 316 IPR045254

Functions

Description
EC Number 3.5.1.128 In linear amides
Subcellular Localization
  • Cytoplasm
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name Definition
deaminated glutathione amidase activity Catalysis of the reaction: N-(4-oxoglutarate)-L-cysteinylglycine + H2O = 2-oxoglutarate + L-cysteinylglycine.

1 GO annotations of biological process

Name Definition
nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q86X76 NIT1 Deaminated glutathione amidase Homo sapiens (Human) PR
10 20 30 40 50 60
MLGFIIRPPH QLLSLLSCPG LRIPRFSVLC APPRLRTMAA SSSFSELPLV AVCQVTSTPD
70 80 90 100 110 120
KEQNFKTCAE LIREAARLGA CLAFLPEAFD FIARDPEETR RLSEPLSGNL LEEYTQLARE
130 140 150 160 170 180
CGLWLSLGGF HERGQDWEQT QKIYNCHVIM NNMGSVVATY RKTHLCDVEI PGQGPMRESN
190 200 210 220 230 240
STIPGPSLES PISTPAGKIG LAICYDMRFP ELSLALVQAG AEILTYPSAF GSVTGPAHWE
250 260 270 280 290 300
VLLRARAIET QCYVVAAAQC GRHHEKRASY GHSMVVDPWG TVVARCSEGP GLCLARIDLN
310 320
YLQQLRKQLP VFQHRRPDLY GNLGHPLS