Q32L17
Gene name |
SPZ1 |
Protein name |
Spermatogenic leucine zipper protein 1 |
Names |
|
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:519496 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q32L17
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q32L17-F1 | Predicted | AlphaFoldDB |
92 variants for Q32L17
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs210566643 | 10 | R>L | No | EVA | |
| rs446935882 | 21 | D>G | No | EVA | |
| rs446935882 | 21 | D>V | No | EVA | |
| rs135710088 | 22 | L>P | No | EVA | |
| rs517373973 | 26 | I>V | No | EVA | |
| rs449358889 | 45 | L>P | No | EVA | |
| rs133319980 | 88 | P>H | No | EVA | |
| rs464161623 | 92 | T>S | No | EVA | |
| rs208032312 | 93 | N>H | No | EVA | |
| rs432732127 | 96 | E>G | No | EVA | |
| rs716631233 | 98 | S>L | No | EVA | |
| rs473058458 | 101 | R>I | No | EVA | |
| rs455505428 | 106 | E>D | No | EVA | |
| rs435301401 | 106 | E>K | No | EVA | |
| rs475642738 | 107 | L>I | No | EVA | |
| rs451546636 | 108 | D>V | No | EVA | |
| rs444310309 | 108 | D>Y | No | EVA | |
| rs721140370 | 109 | E>K | No | EVA | |
| rs471710461 | 111 | N>K | No | EVA | |
| rs440352275 | 113 | E>K | No | EVA | |
| rs460389515 | 114 | L>I | No | EVA | |
| rs442915234 | 115 | V>G | No | EVA | |
| rs480490320 | 115 | V>L | No | EVA | |
| rs453736629 | 116 | K>E | No | EVA | |
| rs465584788 | 120 | A>G | No | EVA | |
| rs465584788 | 120 | A>V | No | EVA | |
| rs470705363 | 122 | L>F | No | EVA | |
| rs479376173 | 122 | L>V | No | EVA | |
| rs446430783 | 124 | L>V | No | EVA | |
| rs381831029 | 126 | K>E | No | EVA | |
| rs137619483 | 127 | K>T | No | EVA | |
| rs469198777 | 129 | N>K | No | EVA | |
| rs455468529 | 129 | N>Y | No | EVA | |
| rs437737900 | 130 | A>E | No | EVA | |
| rs451489328 | 131 | K>Q | No | EVA | |
| rs471637559 | 132 | K>E | No | EVA | |
| rs440282973 | 136 | R>M | No | EVA | |
| rs453955783 | 137 | L>V | No | EVA | |
| rs474047176 | 138 | D>A | No | EVA | |
| rs442878478 | 139 | N>D | No | EVA | |
| rs209435074 | 140 | Q>E | No | EVA | |
| rs462844663 | 141 | N>D | No | EVA | |
| rs483174632 | 144 | D>E | No | EVA | |
| rs134369948 | 152 | D>G | No | EVA | |
| rs459168223 | 154 | V>I | No | EVA | |
| rs441754795 | 156 | C>S | No | EVA | |
| rs479331691 | 156 | C>Y | No | EVA | |
| rs466557870 | 160 | Q>H | No | EVA | |
| rs480258764 | 161 | K>E | No | EVA | |
| rs448903778 | 161 | K>I | No | EVA | |
| rs469009323 | 161 | K>N | No | EVA | |
| rs437704739 | 162 | A>S | No | EVA | |
| rs451364922 | 172 | K>N | No | EVA | |
| rs465195749 | 173 | A>S | No | EVA | |
| rs132649417 | 179 | H>R | No | EVA | |
| rs473911269 | 185 | I>M | No | EVA | |
| rs385668005 | 185 | I>T | No | EVA | |
| rs436314554 | 192 | E>K | No | EVA | |
| rs476697910 | 194 | L>* | No | EVA | |
| rs456534898 | 194 | L>I | No | EVA | |
| rs438916739 | 198 | A>S | No | EVA | |
| rs459066633 | 202 | S>R | No | EVA | |
| rs207669008 | 203 | V>M | No | EVA | |
| rs472827845 | 207 | E>D | No | EVA | |
| rs441536045 | 212 | I>L | No | EVA | |
| rs461594987 | 213 | K>* | No | EVA | |
| rs481725231 | 217 | K>T | No | EVA | |
| rs448864731 | 218 | S>P | No | EVA | |
| rs462569676 | 222 | I>M | No | EVA | |
| rs482762722 | 225 | L>P | No | EVA | |
| rs444961631 | 229 | G>V | No | EVA | |
| rs465122826 | 231 | H>Q | No | EVA | |
| rs433707981 | 232 | S>P | No | EVA | |
| rs447410698 | 234 | T>S | No | EVA | |
| rs436273922 | 235 | Q>K | No | EVA | |
| rs136172097 | 237 | N>K | No | EVA | |
| rs432464979 | 243 | Q>E | No | EVA | |
| rs477714286 | 246 | E>* | No | EVA | |
| rs452623476 | 249 | V>L | No | EVA | |
| rs472690192 | 250 | K>Q | No | EVA | |
| rs381698003 | 257 | Y>H | No | EVA | |
| rs134636935 | 274 | E>K | No | EVA | |
| rs475269053 | 282 | E>V | No | EVA | |
| rs443942573 | 285 | H>L | No | EVA | |
| rs210900059 | 288 | E>Q | No | EVA | |
| rs462505464 | 297 | Q>H | No | EVA | |
| rs444797880 | 305 | K>T | No | EVA | |
| rs516039334 | 329 | F>L | No | EVA | |
| rs478529607 | 333 | D>V | No | EVA | |
| rs447371738 | 337 | T>I | No | EVA | |
| rs523821388 | 355 | R>H | No | EVA | |
| rs467431465 | 370 | L>* | No | EVA |
No associated diseases with Q32L17
No regional properties for Q32L17
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q32L17 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEVPTLSKTR | KPPDLNEESL | DLGIMIALFE | IGSIPPVSCS | SLPSLKSSDH | EATEQRIAKK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FESLLKEIKD | IVKHVTSYEQ | KVTETKEPFK | ETNMFEVSEL | REKIIELDEI | NKELVKKLLA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SLDLGKKENA | KKQEMRLDNQ | NSEDTVQDCS | GDLVNCSKGQ | KALPETQLSK | EKAKHGFPHI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QEENIRLRNN | MERLLQEAEH | WSVEHTELSK | LIKSYQKSQN | DIKTLKNNGT | HSPTQTNNES |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AKQELEEQVK | RLKEDTYSLH | LIATLLENEC | QILEQRVELL | DELHHQKEEP | LQGEPMQINH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EQSDKEQKLP | EAEKVKIHEK | NMPEVEGTFH | KRDQFFTSLD | ICHNKKAHNN | QFNTRIAKRA |
| 370 | |||||
| LVVKRPASSL | S |