Q323U7

PR
Gene name
mdfA (cmr, SBO_0738)
Protein name
Multidrug transporter MdfA
Names
Species
Shigella boydii serotype 4 (strain Sb227)
KEGG Pathway
sbo:SBO_0738
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-40 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q323U7

Entry ID Method Resolution Chain Position Source
AF-Q323U7-F1 Predicted AlphaFoldDB

No variants for Q323U7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q323U7

No associated diseases with Q323U7

2 regional properties for Q323U7

Type Name Position InterPro Accession
conserved_site Sugar transporter, conserved site 72 - 88 IPR005829
domain Major facilitator superfamily domain 14 - 405 IPR020846

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
response to antibiotic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQNKLASGAR LGRQALLFPL CLVLYEFSTY IGADMIQPGM LAVVEQYQAG IDWVPTSMTA
70 80 90 100 110 120
YLAGGMFLQW LLGPLSDRIG RRPVMLAGVV WFIITCLAIL LAQNIEQFTL LRFLQGISLC
130 140 150 160 170 180
FIGAVGYAAI QESFEEAVCI KITALMANVA LIAPLLGPLV GAAWIHVLPW EGMFVLFAAL
190 200 210 220 230 240
AAISFFGLQR AMPETATRIG EKLSLKELGR DYKLVLKNGR FVAGALALGF VSLPLLAWIA
250 260 270 280 290 300
QSPIIIITGE QLSSYEYGLL QVPIFGALIA GNLLLARLTS RRTVRSLIIM GGWPIMIGLL
310 320 330 340 350 360
VAAAATVISS HAYLWMTAGL SIYAFGIGLA NAGLVRLTLF ASDMSKGTVS AAMGMLQMLI
370 380 390 400
FTVGIEISKH AWLNGGNGQF NLFNLVNGIL WLSLMVIFLK DKQMGNSHEG