Q31G65
Gene name |
tilS |
Protein name |
tRNA(Ile)-lysidine synthase |
Names |
tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase |
Species |
Hydrogenovibrio crunogenus (strain DSM 25203 / XCL-2) (Thiomicrospira crunogena) |
KEGG Pathway |
tcx:Tcr_1263 |
EC number |
6.3.4.19: Other carbon--nitrogen ligases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q31G65
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q31G65-F1 | Predicted | AlphaFoldDB |
No variants for Q31G65
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q31G65 | |||||
No associated diseases with Q31G65
8 regional properties for Q31G65
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Immunoglobulin subtype 2 | 260 - 328 | IPR003598-1 |
| domain | Immunoglobulin subtype 2 | 359 - 428 | IPR003598-2 |
| domain | Immunoglobulin subtype | 254 - 339 | IPR003599-1 |
| domain | Immunoglobulin subtype | 353 - 439 | IPR003599-2 |
| domain | Immunoglobulin-like domain | 248 - 333 | IPR007110-1 |
| domain | Immunoglobulin-like domain | 347 - 439 | IPR007110-2 |
| domain | Immunoglobulin I-set | 248 - 338 | IPR013098-1 |
| domain | Immunoglobulin I-set | 347 - 438 | IPR013098-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 6.3.4.19 | Other carbon--nitrogen ligases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ligase activity, forming carbon-nitrogen bonds | Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA modification | The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSYQKVELAI | SKLIHLYPSP | VQFLVAFSGG | LDSTVMLDAL | CKHVSPQSIH | AVYINHGLQP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ESNQWADACK | KACERLGVKF | ESVDVQVSDI | SRQGIEAVAR | QKRYEALYSR | VTKGTILLTA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HHQRDQAETL | LLNMARGAGI | SGLSGMPYVK | NIQLNEQTLQ | HCRPLLNVDY | DAIQSYAKQY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RLDWVEDSSN | QELDYRRNYL | RHEVLPKIRH | AWPFSDANFA | KSAHHLNESL | ALLNELAEID |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LQHTDYTDFY | LSFTNVKELR | WSRLKNMTRY | WTESYVSGLR | LNAKIYQWLQ | ECLNNKNPQA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KPKMLLARGE | LRFYNHVLYY | FDDLKVHYCL | AFDEFDASAL | QLFKALDFSE | QLSSKQGGKL |
| 370 | 380 | 390 | 400 | 410 | |
| EGTVVRPLNP | NDLSSGSQKK | ALKKWFKESK | VPEWDRQRWP | VLEKEGQVVA | ILGFYTKKSF |