Q30ZX3

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20) (Desulfovibrio alaskensis)
KEGG Pathway
dde:Dde_1976
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

791-900 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q30ZX3

Entry ID Method Resolution Chain Position Source
AF-Q30ZX3-F1 Predicted AlphaFoldDB

No variants for Q30ZX3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q30ZX3

No associated diseases with Q30ZX3

5 regional properties for Q30ZX3

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 631 - 823 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 9 - 120 IPR007695
domain DNA mismatch repair protein MutS, core 275 - 614 IPR007696
domain DNA mismatch repair protein MutS, connector domain 130 - 257 IPR007860
domain DNA mismatch repair protein MutS, clamp 451 - 541 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTSHSPKLTP MFEQYMNIKA EYPDALLFYR MGDFYELFFE DAEVAARELQ IALTCRNPNA
70 80 90 100 110 120
ENKVPMCGVP HHSARSYISQ LVDKGYKVAI CEQMEDPREA KGLVKRGVIR VLTSGTALED
130 140 150 160 170 180
ENLSPKAHTY LGALCWDKSE GAGGFAWVDF STGEWSGLQS RKEQELWQWV QKMAPRELLL
190 200 210 220 230 240
ADTLTPPASL ELTETQFSKV PERAYFDYKR SAEKIMSAQQ VAELGALGLE NRKELVRACG
250 260 270 280 290 300
ALLTYLSQTQ KQDLNHLCQF KPLNLNRHLL LDEITERNLE LFRRLDGRKG KGTLWHVLDH
310 320 330 340 350 360
TVTPMGGRLL QERLKHPWRE QAPIDETQEA VSHFFAHNTL RRQLREALDT VYDIERLSTR
370 380 390 400 410 420
IFLNRATPRD YVALRQSLKA LPAVRELLEA PQTGDGRYAT PEEQLGAALP PFLHRMLKSW
430 440 450 460 470 480
DDLADYHDLL EKALVDNPPH VITEGGLFRQ GFHPALDELM DLSEHGASKL HDLLAEVQQT
490 500 510 520 530 540
TGISKIKLGN NRVFGYYFEV PKSVSEELPD TFVRRQTLAN AERYTSERLK ELEEKLFSAA
550 560 570 580 590 600
DKRKTMELKL FQQLREHVAQ ARPRVLFMAD LLATLDHWQG LAEAARHWNW VRPVLHDGQD
610 620 630 640 650 660
IVIREGRHPV VEAVQGPAGF IPNDLRIDDQ RRLLLITGPN MAGKSTVLRQ AAIICILAQI
670 680 690 700 710 720
GSFVPAREAR IGLCDRIFSR VGASDNLAQG QSTFMVEMME TARILRQATR RSLVILDEIG
730 740 750 760 770 780
RGTSTFDGLA LAWAVVEELM KKQQAGIRTL FATHYHELTS LEGTIPGVHN MNIAIKEWGG
790 800 810 820 830 840
EIVFLRRLVP GPSDRSYGVE VAKLAGVPQN VVQRARQILE LLEQKSKADG TRRPASYHEA
850 860 870 880 890 900
QPLLPGMPEP PSTASAEPPQ TVTPPEPPVL TALRDLDTDN LTPLEALTVL TEWKTLWGAG
KNEC