Q30WI5

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20) (Desulfovibrio alaskensis)
KEGG Pathway
dde:Dde_3167
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

676-750 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q30WI5

Entry ID Method Resolution Chain Position Source
AF-Q30WI5-F1 Predicted AlphaFoldDB

No variants for Q30WI5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q30WI5

No associated diseases with Q30WI5

9 regional properties for Q30WI5

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 17 - 147 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 331 - 462 IPR001247-2
domain S1 domain 625 - 695 IPR003029
domain K Homology domain 558 - 623 IPR004087
domain K Homology domain, type 1 564 - 619 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 150 - 213 IPR015847-1
domain Exoribonuclease, phosphorolytic domain 2 465 - 534 IPR015847-2
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 244 - 327 IPR015848
domain RNA-binding domain, S1 626 - 695 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MENLFGAKRL TATVGGKEII METGRLANQA DGAVWIQCGG TVVLCTVCTQ PLEREISFFP
70 80 90 100 110 120
LVVDYTEKMY AAGRIPGSFF RREIGRPSER ETLVSRLIDR PLRPLFPKGF TNEVQILANV
130 140 150 160 170 180
ISADQENDSD VLALCGSSAA VMLSSVPFEA PVAGARVCRI DGEFVLNPTI TEAAKADLNL
190 200 210 220 230 240
VVAANRDALV MVEGEADFVP EEVIAQALEW AHREVQPIID MQEKLRELAG KAKIEFVAPE
250 260 270 280 290 300
EDTELKEKAE ALATADLAAA LQVREKMARK EAKKAVKEKV KAALLQDPAF AETPERLAAL
310 320 330 340 350 360
GDILSSLEKR IVRQRILKEG LRIDGRDTKT VRPIIIEAGA LPRAHGSAIF SRGETKSLVV
370 380 390 400 410 420
TTLGSTTDEQ RMDSLTGDVT KRFMLHYNFP PYSVGEVKPV RVSRREIGHG ALAERALRPV
430 440 450 460 470 480
LPSPDSFPFT LRVVSETMES NGSSSMAAVC GGSLSLMDAG VPVKAPVAGI AMGLIKEDDQ
490 500 510 520 530 540
FIVLTDILGD EDALGDMDFK IAGTAEGVTA VQMDIKIDGL PAEVMGRALA QAREARLHIL
550 560 570 580 590 600
NEMAKVLPEP RQALSKYAPQ LSVVEVNPEI IRVIIGPGGK NIKAITSATG ASIDIEDSGR
610 620 630 640 650 660
ISIFAPTKES MDMAREMVMY YDQRPELGKN YTAKVRKIME IGAIVEILPN CEALIHISQL
670 680 690 700 710 720
DTSRVEKTED VVQLGQDVEV KVIEINDGRV RASRKAVMLE AQGVEWDPAD TARPPRKPRD
730 740
RDDRGDRGGR GDRGDRGGRN GRGGDRRDRR