Q2YUH3

PR
Gene name
cshA
Protein name
DEAD-box ATP-dependent RNA helicase CshA
Names
Species
Staphylococcus aureus (strain bovine RF122 / ET3-1)
KEGG Pathway
sab:SAB1965c
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-60 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2YUH3

Entry ID Method Resolution Chain Position Source
AF-Q2YUH3-F1 Predicted AlphaFoldDB

No variants for Q2YUH3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2YUH3

No associated diseases with Q2YUH3

5 regional properties for Q2YUH3

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 148 - 156 IPR000629
domain Helicase, C-terminal 214 - 375 IPR001650
domain DEAD/DEAH box helicase domain 26 - 191 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 21 - 218 IPR014001
domain RNA helicase, DEAD-box type, Q motif 2 - 30 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

2 GO annotations of biological process

Name Definition
RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
RNA secondary structure unwinding The process in which a secondary structure of RNA are broken or 'melted'.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQNFKELGIS DNTVQSLESM GFKEPTPIQK DSIPYALQGI DILGQAQTGT GKTGAFGIPL
70 80 90 100 110 120
IEKVVWKQGV QSLILAPTRE LAMQVAEQLR EFSRGQGVQV VTVFGGMPIE RQIKALKKGP
130 140 150 160 170 180
QIVVGTPGRV IDHLNRRTLK TDGIHTLILD EADEMMNMGF IDDMRFIMDK IPAVQRQTML
190 200 210 220 230 240
FSATMPKAIQ ALVQQFMKSP KIIKTMNNEM SDPQIEEFYT IVKELEKFDT FTNFLDVHQP
250 260 270 280 290 300
ELAIVFGRTK RRVDELTSAL ISKGYKAEGL HGDITQAKRL EVLKKFKNDQ INILVATDVA
310 320 330 340 350 360
ARGLDISGVS HVYNFDIPQD TESYTHRIGR TGRAGKEGIA VTFVNPIEMD YIRQIEDANG
370 380 390 400 410 420
RKMSALRPPH RKEVLQARED DIKEKVENWM SKESESRLKR ISTELLNEYN DVDLVAALLQ
430 440 450 460 470 480
ELVEANDEVE VQLTFEKPLS RKGRNGKPSG SRNRNSKRGN PKFDSKSKRS KGYSSKKKST
490 500
KKFDRKEKSS GGSRPMKGRT FADHQK