Q2YBJ8
Gene name |
thrB |
Protein name |
Homoserine kinase |
Names |
HK, HSK |
Species |
Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71) |
KEGG Pathway |
nmu:Nmul_A0565 |
EC number |
2.7.1.39: Phosphotransferases with an alcohol group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2YBJ8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2YBJ8-F1 | Predicted | AlphaFoldDB |
No variants for Q2YBJ8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2YBJ8 | |||||
No associated diseases with Q2YBJ8
7 regional properties for Q2YBJ8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) | 318 - 528 | IPR002314 |
| domain | TGS | 1 - 61 | IPR004095 |
| domain | Anticodon-binding | 540 - 628 | IPR004154 |
| domain | Aminoacyl-tRNA synthetase, class II | 242 - 533 | IPR006195 |
| domain | Threonyl/alanyl tRNA synthetase, SAD | 169 - 218 | IPR012947 |
| domain | Threonine-tRNA ligase catalytic core domain | 241 - 538 | IPR033728 |
| domain | Threonine-tRNA ligase, class IIa, anticodon-binding domain | 538 - 628 | IPR047246 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.1.39 | Phosphotransferases with an alcohol group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| homoserine kinase activity | Catalysis of the reaction: L-homoserine + ATP = O-phospho-L-homoserine + ADP + 2 H(+). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
| threonine biosynthetic process | The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSVFTIVTHE | QLSAWLRNYS | IGKLVNLQGI | SSGIENTNYF | VTTSHGKYVL | TLFEKLTSAE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LPYYLNLMAY | LARHGLPCPS | PVADLANKFL | GELNGKPASI | VTCLPGKSQE | SPTATHCAEV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GELLANMHLS | GLSYPEKMEN | LRGPRWWKAA | AQEVMPFLSE | DEAAILGEEL | RFQSSHRTES |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LPRGVIHADL | FRDNVLFKDG | AMGGVIDFYF | ACNDVLLYDL | AITANDWCLN | ENAELDPERT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LSLLEAYHRT | RPLLEIERDA | WPVMLRAGAL | RFWLSRLQDY | HLPRAGELTH | VKDPAHFMRI |
| 310 | |||||
| LQSHAAARSK | LAEVWI |