Q2YB94

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)
KEGG Pathway
nmu:Nmul_A0670
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

799-896 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2YB94

Entry ID Method Resolution Chain Position Source
AF-Q2YB94-F1 Predicted AlphaFoldDB

No variants for Q2YB94

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2YB94

No associated diseases with Q2YB94

5 regional properties for Q2YB94

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 640 - 830 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 24 - 135 IPR007695
domain DNA mismatch repair protein MutS, core 288 - 621 IPR007696
domain DNA mismatch repair protein MutS, connector domain 152 - 272 IPR007860
domain DNA mismatch repair protein MutS, clamp 458 - 548 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQSSKARLS TDPTVFEAVL NNHTPMMQQY LRIKAQHPDM LMFYRMGDFY ELFFDDAEKA
70 80 90 100 110 120
AKLLDITLTR RGTSAGEPIK MAGVPYHAAE QYLAKLVKLG ESVVICEQVG DPATSKGPVE
130 140 150 160 170 180
RQVTRIITPG TLTDAALLED KRDSALLALL VHESTLGLAW LNLAAGQFSV METSVNNLTA
190 200 210 220 230 240
ELERLKPAEI LLPESLNLAG INDRVIQEKL CVKHLPAWQF DTAAAVRNLS RQFGTHDLSG
250 260 270 280 290 300
FGCEDLDVSL GAASALLDYT RLTQGASIGH IKGLRVERED TYLRMDATTR RNLEISETIR
310 320 330 340 350 360
GDAAPTLLSL LDTCSTNMGS RLLCHWLHHP LRDRGLIQNR LNGVSFLMGE AGSGPCLSVR
370 380 390 400 410 420
DCLKRVTDIE RITARIALKS ARPRDLSGLR DSLKRLPAVN NAVAGTATTS SGGSDVSAHV
430 440 450 460 470 480
AALIHSMAPD NALVALLEKS LKEEPEVMLR TGGVIADGYD AELDELRAIH NNCDEFLLQL
490 500 510 520 530 540
ETREKARTGI ANLKVEYNRL HGFYIEVTHA HTEKIPDDYR RRQTLKNAER YITPELKAFE
550 560 570 580 590 600
EKALSAQSRA LEREKLLYGE LLDMLSQYID HLQQVARSVA ELDVLATFAE RALALDYSLP
610 620 630 640 650 660
LFTSDSVIEI QAGRHPVVEK QVDSFIANDV QLGARTGGRR QMLVITGPNM GGKSTYMRQV
670 680 690 700 710 720
ALIALLAHCG SFVPARSALI GPLDQLFTRI GASDDLAGGR STFMMEMTEA ANILHNATAQ
730 740 750 760 770 780
SLVLMDEVGR GTSTFDGLAL AFAIARYLLE KNRSYTLFAT HYFELTRLAE EFAQVANVHL
790 800 810 820 830 840
RAVEHKHHIV FLHAVNEGPA SQSYGLQVAA LAGVPDPVIR TARRYLLKLE QEALSNQPQG
850 860 870 880 890 900
DLFSRDDLFW KQDRMPEGSV DKNDSAPEHP VLALLRTIVP DDLSPKQALE QLYGLKKAAE
KE