Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2UUT6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2UUT6-F1 | Predicted | AlphaFoldDB |
No variants for Q2UUT6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2UUT6 | |||||
No associated diseases with Q2UUT6
No regional properties for Q2UUT6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q2UUT6 | |||
Functions
7 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasmic vesicle membrane | The lipid bilayer surrounding a cytoplasmic vesicle. |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| phagophore | A disk-like structure that expands, rounds up into a cup-shaped structure, and eventually closes around its cargo (for example cytoplasmic components) to become an autophagosome or Cvt vesicle. |
| phagophore assembly site membrane | A cellular membrane associated with the phagophore assembly site. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| phospholipid scramblase activity | Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| autophagy of mitochondrion | The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions. |
| late nucleophagy | A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM. |
| piecemeal microautophagy of the nucleus | Degradation of a cell nucleus by lysosomal microautophagy. |
| protein localization to phagophore assembly site | Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS). |
| reticulophagy | The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMTSNILSRF | LPPNGSPSVY | ETLRQQDAES | NPSDVEERAG | LEFEDDRRTQ | FSDRELEEAM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VDAARDGIRS | PSPSPSEPFL | TQRSPQRTSG | TATAKTGGRR | RKHSRPRWMH | QDPDDGDDDV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PPSLLVEGHQ | DDDEMRSRLP | PPPPSHRHPQ | RELSPAPGPS | SRADRARWNT | TREQLPLHND |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GRGQRPGVIW | SLGHPNLASV | DPKEKAMWLW | ANVENLDNFL | KDVYTYFLGN | GIWSILLNRG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LSLLTFAFVV | GFSTFLTNCI | DYRNFRGSRK | MDDILIQQCT | KKMSMSSTFL | LWLLTVFWIG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KAFQYLMDIR | RLKHMHDFYY | YLLGISDSEI | QTISWQEVVS | RLMTLRDANP | ATAGAVSARH |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RKFMGSQSKQ | RMDAHDIANR | LMRKENYLIA | LVNKDILDLT | LPIPFLRNRQ | LFSQTLEWNI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NLCIMDYVFN | DQGQVRTLFL | KDTHRKALSE | GLRRRFIFAG | IMNIFVAPFI | VVYFLMHYFF |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RYFNEYKKNP | AQIGSRQYTP | LAEWKFREFN | ELWHLFERRV | NMSYPFASRY | VDQFPKDKTV |
| 550 | 560 | 570 | 580 | 590 | 600 |
| QVAGFVAFVS | GALASVLALV | SIIDPELFLG | FEITHDRTVL | FYLGVFGSVW | AFARGLVPEE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TNVFDPEFAL | LEVIDFTHYF | PNHWKGRLHS | DEVRKEFAVL | YQMKIVIFLE | EILSMIFTPF |
| 670 | 680 | 690 | 700 | 710 | 720 |
| ILWFSLPKCS | DRLIDFFREF | TVHVDGMGYL | CSFAVFDFKK | GTNVISQGGT | GRRESGRQDL |
| 730 | 740 | 750 | 760 | 770 | 780 |
| RADYFSTKDG | KMLASYYGFL | DNYGGNRPAN | PSSRRQFHPP | PAFPTLGSPS | AIEMGNIGER |
| 790 | 800 | 810 | 820 | 830 | 840 |
| LERTQTRHGP | AATFMGQQSG | LGPGFGAAGF | GDHASPAPSI | LLDPHHQPTA | SDFRTANRSA |
| 850 | 860 | 870 | 880 | 890 | 900 |
| LYPRFRSSRP | VRPITDPIED | DNESPSAEIR | RGAVKKSPHT | TTGSSGGAIG | TSDSNLGESW |
| 910 | 920 | 930 | 940 | 950 | |
| RMNLIGDELD | KDTGEDGENV | DEIAGNAGVL | GLIQQFQKVS | KDNRGRTTVG | I |