Q2UQH4

PR
Gene name
gwt1 (AO090005001245)
Protein name
GPI-anchored wall transfer protein 1
Names
Species
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
KEGG Pathway
aor:AO090005001245
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

72-154 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2UQH4

Entry ID Method Resolution Chain Position Source
AF-Q2UQH4-F1 Predicted AlphaFoldDB

No variants for Q2UQH4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2UQH4

No associated diseases with Q2UQH4

2 regional properties for Q2UQH4

Type Name Position InterPro Accession
domain IMP dehydrogenase/GMP reductase 8 - 317 IPR001093
conserved_site IMP dehydrogenase / GMP reductase, conserved site 166 - 178 IPR015875

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
glucosaminyl-phosphatidylinositol O-acyltransferase activity Catalysis of the reaction: glucosaminyl-phosphatidylinositol + fatty acyl-CoA = glucosaminyl-acyl-phasphotidylinositol + CoA.

1 GO annotations of biological process

Name Definition
GPI anchor biosynthetic process The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDSSYKARKE AFVSNLAGGS ILEINAVTLV APTSVLLWSV LQSRLSFFIP YGALALVTDF
70 80 90 100 110 120
FLNVLPILFA TTLYSSAPWT LNILLALPAL ILLFTSTPSR TQQKAKPPRP SAAAKKNTPK
130 140 150 160 170 180
HASDSPEPLP VHPFLTTYRA AMMVITCVAI LAVDFRIFPR RFAKAENWGT SLMDLGVGSF
190 200 210 220 230 240
VFSSGVVSAR SILKGRNSHS KKAGLWQRLA ASARHSIPLL VLGLVRLYSV KGLDYAEHVT
250 260 270 280 290 300
EYGVHWNFFF TLGLLPPFVE IFDALAAIIP SYEILSLGIV VLYQVALEST DLKSYILVSP
310 320 330 340 350 360
RGPDLLSKNR EGVFSFLGYL AIFLTGRAIG IRIIPRGTSA SRSPQQARKS VLISLGLQTL
370 380 390 400 410 420
VWTTLFVFNS THAMGLGAGI PVSRRLANMP YVLWVSAFNN AQLFLFCLLE STFFPSIHRE
430 440 450 460 470 480
TGKDGELERT SFATSRIMTA FNKNGLALFL VANLLTGAVN LSVPTLDVTT AHAMVVLIAY
490
VAMITGVALA LDRANIKLSL