Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q2UNK6

Entry ID Method Resolution Chain Position Source
AF-Q2UNK6-F1 Predicted AlphaFoldDB

No variants for Q2UNK6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2UNK6

No associated diseases with Q2UNK6

2 regional properties for Q2UNK6

Type Name Position InterPro Accession
domain GB1/RHD3-type guanine nucleotide-binding (G) domain 50 - 300 IPR030386
domain Sey1/RHD3-like, three-helix bundle domain 363 - 801 IPR046758

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
  • Enriched in the cortical ER
  • Concentrated in punctae along the ER tubules
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cortical endoplasmic reticulum A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements.
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

2 GO annotations of biological process

Name Definition
endoplasmic reticulum inheritance The partitioning of endoplasmic reticulum between daughter cells at cell division.
endoplasmic reticulum membrane fusion The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATNGHFASI GNSASDTTAY EHGVQVIDEN KEFKNPNLSQ YLSLENVTPS GFNYHLISVF
70 80 90 100 110 120
GSQSTGKSTL LNHLFGTHFS VMSELERRQT TKGIWMSKNK NESSSMASNI LVMDVEGTDG
130 140 150 160 170 180
RERGEDQDFE RKSALFALAT SEVLIVNIWE HQVGLYQGAN MGLLKTVFEV NLQLFLKDKN
190 200 210 220 230 240
TTHRSLLFFV IRDYSGMTPL QNLQKTLMED MARLWDSISK PGGLENSNVH DYFDFQFYGL
250 260 270 280 290 300
PHKGYQPEKF VEETQKLSLR FCDGQRDPNL DARKGEFSDG GVFLPEYHRR IPADGFSRYA
310 320 330 340 350 360
EGIWDQIVNN KDLDLPTQQE LLAQFRCDEI LREVMVAFDE TIVPFEDKQS QAARLGEPEI
370 380 390 400 410 420
LGGLGAAMRS SRTKAVKAFE SEASRYHKGV YQRKRAELES KADTRLKTLF QGQLNAAHKS
430 440 450 460 470 480
GISEFSEAVT AAVKSGQKKG TGYDFAEIVN EEAKKAVDKF EEVARATVVD GTSWSDYKQE
490 500 510 520 530 540
LALYEKELAE VSARLRRDEM RRLASRVERW VQSRLGESVG LEFNALGSGR AGGGAPEKGD
550 560 570 580 590 600
QPTEKKFWDR VWNVFVETVL DAERRFTDRA SSFDASLEEV DVGLWRLRRK SWGVLRAKID
610 620 630 640 650 660
EEMIEGNLLL KLRENFEDKF RYDDAGVPRI WRPTDDIEGI YTRARESTLT LIPLLSKFRL
670 680 690 700 710 720
DETSAPPPLD RWIGHTPSSA TSADEEDLAP IGGVDEEEGK SLEEEMTIVS DAKRQELTVR
730 740 750 760 770 780
FKKAADGVYV EAKRSAIGGM TQVPLYFYGL LLALGWNEII AVLRNPAYFF LLFVCAVGAY
790 800 810 820 830 840
ITYQLNLWGP IIKMTEAASN QAVTEGKKRL REFLESSDTG RQAIAMSTPG GSGRGGEEHE
850
MSRLNQQGKS AAADEDVDDL