Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q2UD74

Entry ID Method Resolution Chain Position Source
AF-Q2UD74-F1 Predicted AlphaFoldDB

No variants for Q2UD74

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2UD74

No associated diseases with Q2UD74

1 regional properties for Q2UD74

Type Name Position InterPro Accession
domain Major facilitator superfamily domain 378 - 607 IPR020846

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane ; Multi-pass membrane protein
  • Vacuole and punctate structures
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

1 GO annotations of molecular function

Name Definition
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

2 GO annotations of biological process

Name Definition
amino acid transmembrane export from vacuole The directed movement of amino acids out of the vacuole, across the vacuolar membrane.
autophagy The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTVAPPSPNS PAAELQQRPP RYPGEDTTPT SKREIWGWYA YGIAAEVFAV CGVGSFLPLT
70 80 90 100 110 120
LEQLAREQGT FKSSHLPCVG PGSPSTSVNG TAPAMLRRDE AENDQCVVGL LGLNINTASF
130 140 150 160 170 180
AMYTFSLAVL VQALTLISFS ALADYENNRK TLLLAFGFIG SATSMLFVFI APPIFVLGAL
190 200 210 220 230 240
LVVIGVTCLG SSFVVLNSFL PVLVANDPSI EKASKPAEEL HPMSPDGEYI HPRDSFSASD
250 260 270 280 290 300
AESGPHPAAE AGSGTSSGPA SPELQLSTRI SSKGVGLGYC AAVLVQILSI SLLFTLSKTS
310 320 330 340 350 360
ISKVSGTLPL RFVLLLVGIW WFSFTMVTRK WLRARPGPPL NTANTGGQVK RWRVWLRLVG
370 380 390 400 410 420
FAWKSLWKTV KIAVQLREVL VFLAAWFLLS DAMATVSGTA ILFARTELKM STTLVGLLSI
430 440 450 460 470 480
TATLSGMAGA FLWPVVSRRF GLKSNHTIML CIALFEIIPL YGMLAYIPVF KKWGVIGLQQ
490 500 510 520 530 540
PWEIFPLAIV HGVVSGGLSS YCRSFFGLLI PPGSEAAFYA LYAATDKGSS VIGPAIVGML
550 560 570 580 590 600
IDATGQVRSG FFFIAPLILM PIPLIWIVNA EKGRREGVAM AQRLEKGHET EMSEQTEEAE
GLLARGI