Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2UD74
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2UD74-F1 | Predicted | AlphaFoldDB |
No variants for Q2UD74
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2UD74 | |||||
No associated diseases with Q2UD74
1 regional properties for Q2UD74
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Major facilitator superfamily domain | 378 - 607 | IPR020846 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| vacuolar membrane | The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| amino acid transmembrane export from vacuole | The directed movement of amino acids out of the vacuole, across the vacuolar membrane. |
| autophagy | The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTVAPPSPNS | PAAELQQRPP | RYPGEDTTPT | SKREIWGWYA | YGIAAEVFAV | CGVGSFLPLT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LEQLAREQGT | FKSSHLPCVG | PGSPSTSVNG | TAPAMLRRDE | AENDQCVVGL | LGLNINTASF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AMYTFSLAVL | VQALTLISFS | ALADYENNRK | TLLLAFGFIG | SATSMLFVFI | APPIFVLGAL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LVVIGVTCLG | SSFVVLNSFL | PVLVANDPSI | EKASKPAEEL | HPMSPDGEYI | HPRDSFSASD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AESGPHPAAE | AGSGTSSGPA | SPELQLSTRI | SSKGVGLGYC | AAVLVQILSI | SLLFTLSKTS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ISKVSGTLPL | RFVLLLVGIW | WFSFTMVTRK | WLRARPGPPL | NTANTGGQVK | RWRVWLRLVG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FAWKSLWKTV | KIAVQLREVL | VFLAAWFLLS | DAMATVSGTA | ILFARTELKM | STTLVGLLSI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TATLSGMAGA | FLWPVVSRRF | GLKSNHTIML | CIALFEIIPL | YGMLAYIPVF | KKWGVIGLQQ |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PWEIFPLAIV | HGVVSGGLSS | YCRSFFGLLI | PPGSEAAFYA | LYAATDKGSS | VIGPAIVGML |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IDATGQVRSG | FFFIAPLILM | PIPLIWIVNA | EKGRREGVAM | AQRLEKGHET | EMSEQTEEAE |
| GLLARGI |