Q2UBP1

PR
Gene name
hulA (AO090012000923)
Protein name
Probable E3 ubiquitin-protein ligase hulA
Names
HECT ubiquitin ligase A, HECT-type E3 ubiquitin transferase hulA
Species
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
KEGG Pathway
aor:AO090012000923
EC number
2.3.2.26: Aminoacyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

113-311 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2UBP1

Entry ID Method Resolution Chain Position Source
AF-Q2UBP1-F1 Predicted AlphaFoldDB

No variants for Q2UBP1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2UBP1

No associated diseases with Q2UBP1

5 regional properties for Q2UBP1

Type Name Position InterPro Accession
domain C2 domain 1 - 112 IPR000008
domain HECT domain 461 - 816 IPR000569
domain WW domain 229 - 262 IPR001202-1
domain WW domain 333 - 366 IPR001202-2
domain WW domain 393 - 426 IPR001202-3

Functions

Description
EC Number 2.3.2.26 Aminoacyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
ubiquitin protein ligase activity Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.

1 GO annotations of biological process

Name Definition
ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGSNLPAQPN LRVTIIAADG LYKRDVFRFP DPFAVATVGG EQTHTTSVIK KTLNPYWNEM
70 80 90 100 110 120
FDLRVNEDSI LAIQIFDQKK FKKKDQGFLG VINVRIGDVI DLQMGGDEML TRDLKKSNDN
130 140 150 160 170 180
LVVHGKLIIN LSTNLSTPNT NQANGLHRSH MQPSTSSGLV PQVSASTPQP SPGPSQADPT
190 200 210 220 230 240
ASNPSLHPQR VPSTTRPSST IVPANGPPAP PNGQQGSRTN LSSFEDSQGR LPAGWERRED
250 260 270 280 290 300
NLGRTYYVDH NTRTTTWTRP SNNYNEQTSR TQREASMQLE RRAHQSRMLP EDRTGASSPN
310 320 330 340 350 360
LQENQQQAQT PPAGGSASAV SMMATGATTA GTGELPPGWE QRTTPEGRPY FVDHNTRTTT
370 380 390 400 410 420
WVDPRRQQYI RMYGQNANGT NTTIQQQPVS QLGPLPSGWE MRLTNTARVY FVDHNTKTTT
430 440 450 460 470 480
WDDPRLPSSL DQGVPQYKRD FRRKLIYFRS QPALRIMSGQ CHVKVRRNNI FEDSYAEIMR
490 500 510 520 530 540
QSASDLKKRL MIKFDGEDGL DYGGLSRREF FFLLSHEMFN PFYCLFEYSA HDNYTLQINP
550 560 570 580 590 600
HSGVNPEHLN YFKFIGRVVG LAIFHRRFLD SFFIGAFYKM MLRKKVSLQD MEGVDEDLHR
610 620 630 640 650 660
NLTWTLDNDI EGIIELTFAV DDEKFGERRT IDLKPGGRDI PVTNENKGEY VELVTEWKIV
670 680 690 700 710 720
KRVEEQFNAF MSGFNELIPA DLVNVFDERE LELLIGGIAD IDVDDWKKHT DYRGYQESDE
730 740 750 760 770 780
VIQNFWKIVR TWDAEQKSRL LQFTTGTSRI PVNGFKDLQG SDGPRRFTIE KSGDPGALPK
790 800 810
SHTCFNRLDL PPYKTNDVLE HKLSIAVEET LGFGQE