Q2U100
Gene name |
AO090011000230 |
Protein name |
Mannitol 2-dehydrogenase |
Names |
M2DH, MDH |
Species |
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) |
KEGG Pathway |
aor:AO090011000230 |
EC number |
1.1.1.67: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2U100
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2U100-F1 | Predicted | AlphaFoldDB |
No variants for Q2U100
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2U100 | |||||
No associated diseases with Q2U100
5 regional properties for Q2U100
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Forkhead-associated (FHA) domain | 30 - 98 | IPR000253 |
| domain | Zinc finger, RING-type | 277 - 316 | IPR001841 |
| conserved_site | Zinc finger, RING-type, conserved site | 293 - 302 | IPR017907 |
| domain | Aprataxin and PNK-like factor, PBZ domain | 605 - 628 | IPR019406 |
| domain | E3 ubiquitin-protein ligase CHFR, cysteine rich domain with multizinc binding | 441 - 593 | IPR040909 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.1.1.67 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mannitol 2-dehydrogenase activity | Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAPLKLNNKN | LSQIAAAGET | QVKVPTYKRG | GDVKEGIVHV | GVGGFHRAHL | AVYVDQLMQK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HGVTDYAICG | VGLQPFDAAM | RDALGSQDHL | YTVIERSAKG | SFAHVVGSIN | SYLFAPDNRE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AVIAKMAHPD | THIVSLTITE | SGYYYNENTH | ELQSEHPDIQ | FDLQPANEKS | PRTTFGFLYA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ALARRYQQGL | KPFTVMSCDN | MQKNGSITRH | MLESFARLRN | PEIAKWIAEQ | GAFPNAMVDR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ITPQTSATDK | TALADNFAIE | DSWPVVTEPF | MQWVIEDQFS | DGRPPFEKVG | AQVVKNVHDV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EEFEKHKLRL | LNGSHSAIGY | PGQLAGFKYV | HEVMENPLFS | KFVWQMMQDE | VKPLLPEIPG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VNIDEYCKTL | IERFSNPTIM | DQLPRICLNA | SGKIPQFIMP | SIAEAIWVTG | PFRRLCFVAA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| AWFHYINGVD | DSGKKFEVDD | PMREELQAKA | RAGGTSPAEL | LSIKSLFGDD | LRGDKRFLQE |
| 490 | 500 | ||||
| ITKAMEDIAR | DGILKTLPKY | ID |