Q2TBW5
Gene name |
ZNHIT2 |
Protein name |
Zinc finger HIT domain-containing protein 2 |
Names |
|
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:539138 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2TBW5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2TBW5-F1 | Predicted | AlphaFoldDB |
137 variants for Q2TBW5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs210173012 | 5 | G>V | No | EVA | |
| rs449433925 | 7 | C>F | No | EVA | |
| rs466335191 | 7 | C>S | No | EVA | |
| rs463846004 | 8 | G>C | No | EVA | |
| rs478000173 | 9 | F>S | No | EVA | |
| rs457929945 | 12 | T>A | No | EVA | |
| rs472268941 | 14 | E>G | No | EVA | |
| rs455469852 | 15 | A>S | No | EVA | |
| rs476340132 | 20 | Y>C | No | EVA | |
| rs441783228 | 20 | Y>H | No | EVA | |
| rs456204620 | 21 | T>S | No | EVA | |
| rs432790779 | 21 | T>S | No | EVA | |
| rs453685574 | 22 | C>S | No | EVA | |
| rs435093019 | 22 | C>W | No | EVA | |
| rs449427057 | 24 | R>S | No | EVA | |
| rs470315287 | 27 | V>A | No | EVA | |
| rs435770121 | 27 | V>M | No | EVA | |
| rs450094618 | 31 | S>W | No | EVA | |
| rs447566131 | 33 | R>G | No | EVA | |
| rs478974093 | 34 | C>S | No | EVA | |
| rs441831643 | 38 | H>P | No | EVA | |
| rs462700969 | 40 | S>N | No | EVA | |
| rs439335774 | 41 | C>W | No | EVA | |
| rs453747506 | 46 | Y>F | No | EVA | |
| rs472910385 | 48 | D>A | No | EVA | |
| rs472910385 | 48 | D>G | No | EVA | |
| rs456006827 | 49 | Q>K | No | EVA | |
| rs435832365 | 53 | E>* | No | EVA | |
| rs470407603 | 53 | E>D | No | EVA | |
| rs477786736 | 55 | R>H | No | EVA | |
| rs477786736 | 55 | R>P | No | EVA | |
| rs464469092 | 56 | G>C | No | EVA | |
| rs447629437 | 60 | S>P | No | EVA | |
| rs479043161 | 68 | L>M | No | EVA | |
| rs462066870 | 72 | R>L | No | EVA | |
| rs448371241 | 77 | T>A | No | EVA | |
| rs462762711 | 87 | R>S | No | EVA | |
| rs463975915 | 89 | G>D | No | EVA | |
| rs470711925 | 99 | W>R | No | EVA | |
| rs460219858 | 103 | A>G | No | EVA | |
| rs454396994 | 108 | V>G | No | EVA | |
| rs435900608 | 109 | A>D | No | EVA | |
| rs435900608 | 109 | A>G | No | EVA | |
| rs476907545 | 110 | F>L | No | EVA | |
| rs456597524 | 112 | R>G | No | EVA | |
| rs464532576 | 117 | G>S | No | EVA | |
| rs454072668 | 118 | E>D | No | EVA | |
| rs434024440 | 119 | A>P | No | EVA | |
| rs482990420 | 123 | L>P | No | EVA | |
| rs469250991 | 130 | W>C | No | EVA | |
| rs134253594 | 130 | W>G | No | EVA | |
| rs132767191 | 131 | W>G | No | EVA | |
| rs477190251 | 133 | R>G | No | EVA | |
| rs460283710 | 135 | A>G | No | EVA | |
| rs460283710 | 135 | A>V | No | EVA | |
| rs443968109 | 152 | E>G | No | EVA | |
| rs211523610 | 158 | P>L | No | EVA | |
| rs476738834 | 164 | E>D | No | EVA | |
| rs439808225 | 166 | V>G | No | EVA | |
| rs471011411 | 167 | R>G | No | EVA | |
| rs454204463 | 168 | D>E | No | EVA | |
| rs718825643 | 168 | D>H | No | EVA | |
| rs468621251 | 169 | E>D | No | EVA | |
| rs434087112 | 169 | E>G | No | EVA | |
| rs437972733 | 171 | A>G | No | EVA | |
| rs454947811 | 171 | A>S | No | EVA | |
| rs469314611 | 172 | A>P | No | EVA | |
| rs469314611 | 172 | A>S | No | EVA | |
| rs477255976 | 174 | E>G | No | EVA | |
| rs466778646 | 175 | Q>R | No | EVA | |
| rs446575879 | 176 | V>F | No | EVA | |
| rs460985666 | 179 | D>A | No | EVA | |
| rs444055005 | 179 | D>E | No | EVA | |
| rs481618132 | 180 | L>P | No | EVA | |
| rs471074932 | 183 | A>P | No | EVA | |
| rs440570957 | 184 | C>F | No | EVA | |
| rs454331456 | 184 | C>G | No | EVA | |
| rs454331456 | 184 | C>R | No | EVA | |
| rs440570957 | 184 | C>S | No | EVA | |
| rs475169985 | 184 | C>W | No | EVA | |
| rs454936846 | 185 | P>A | No | EVA | |
| rs454936846 | 185 | P>S | No | EVA | |
| rs454936846 | 185 | P>T | No | EVA | |
| rs475804065 | 186 | P>A | No | EVA | |
| rs432265797 | 190 | T>P | No | EVA | |
| rs446665965 | 191 | R>L | No | EVA | |
| rs436173693 | 193 | P>A | No | EVA | |
| rs467536192 | 195 | L>M | No | EVA | |
| rs450501411 | 196 | A>T | No | EVA | |
| rs458390457 | 199 | S>R | No | EVA | |
| rs460783210 | 203 | T>N | No | EVA | |
| rs477534055 | 203 | T>P | No | EVA | |
| rs475205522 | 205 | P>S | No | EVA | |
| rs475867443 | 207 | V>G | No | EVA | |
| rs432327442 | 209 | F>C | No | EVA | |
| rs452552229 | 209 | F>L | No | EVA | |
| rs436242299 | 220 | H>R | No | EVA | |
| rs467550907 | 221 | T>A | No | EVA | |
| rs467550907 | 221 | T>P | No | EVA | |
| rs450562554 | 222 | L>P | No | EVA | |
| rs436881130 | 226 | H>Y | No | EVA | |
| rs444833881 | 228 | G>C | No | EVA | |
| rs479204040 | 230 | E>D | No | EVA | |
| rs440898828 | 237 | C>W | No | EVA | |
| rs447103404 | 238 | A>S | No | EVA | |
| rs481728965 | 239 | T>A | No | EVA | |
| rs444619632 | 240 | L>P | No | EVA | |
| rs475931170 | 241 | L>P | No | EVA | |
| rs453238562 | 248 | G>D | No | EVA | |
| rs474097390 | 251 | Q>K | No | EVA | |
| rs457001798 | 253 | F>S | No | EVA | |
| rs436942840 | 254 | A>P | No | EVA | |
| rs464937530 | 255 | S>P | No | EVA | |
| rs465736164 | 262 | A>G | No | EVA | |
| rs448834841 | 265 | H>Q | No | EVA | |
| rs481799044 | 268 | E>G | No | EVA | |
| rs468049051 | 271 | E>D | No | EVA | |
| rs451155632 | 272 | H>Q | No | EVA | |
| rs459087513 | 295 | P>R | No | EVA | |
| rs438930615 | 299 | K>N | No | EVA | |
| rs479917920 | 300 | S>R | No | EVA | |
| rs459709629 | 302 | T>S | No | EVA | |
| rs474143341 | 305 | A>G | No | EVA | |
| rs443433712 | 311 | Q>H | No | EVA | |
| rs471412973 | 314 | G>R | No | EVA | |
| rs434495255 | 315 | R>P | No | EVA | |
| rs434495255 | 315 | R>Q | No | EVA | |
| rs451356648 | 315 | R>W | No | EVA | |
| rs455277289 | 320 | A>S | No | EVA | |
| rs435161424 | 348 | D>E | No | EVA | |
| rs468114055 | 349 | A>T | No | EVA | |
| rs519734329 | 367 | A>V | No | EVA | |
| rs42191314 | 370 | D>E | No | EVA | |
| rs482472790 | 371 | V>G | No | EVA | |
| rs465579426 | 390 | R>G | No | EVA | |
| rs445397195 | 395 | E>V | No | EVA | |
| rs479991858 | 397 | L>P | No | EVA |
No associated diseases with Q2TBW5
1 regional properties for Q2TBW5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, HIT-type | 4 - 41 | IPR007529 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9UHR6 | ZNHIT2 | Zinc finger HIT domain-containing protein 2 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEPAGPCGFC | PTGEAQPARY | TCPRCNVPYC | SLRCYRAHGS | CAEEFYRDQV | LGELRGRSAS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PSRLATALRR | LRQQRETEDE | PGDAGLRPGP | APGGLSGLWE | RLAPAEKVAF | ERLLSRGEAG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RLLPPWRPWW | WGRGAGPRLL | EELGDAPSGD | AEELEPSPAR | MPPEPVRDEP | AAVEQVLGDL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PGACPPAVPT | RIPALASLSR | GRTSPLVRFQ | LPNVLFAYAH | TLALYHGGDE | ALLSDFCATL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LGVSGALGAQ | QVFASAEEAL | QAAAHVLEAG | EHPPGPLGTR | GAMREAARIL | LGEGPANQKS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YTLAALGDLA | QTLGRARKQA | VAPEERDRLY | RARKKCQFLL | SWTNENEDAL | TPLALDCATA |
| 370 | 380 | 390 | |||
| HRAHTVAAED | VAALTGELEQ | LWGGPLPPAR | RTLIEELPG |