Q2TBS3
Gene name |
SCP2D1 |
Protein name |
SCP2 sterol-binding domain-containing protein 1 |
Names |
|
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:505971 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2TBS3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2TBS3-F1 | Predicted | AlphaFoldDB |
33 variants for Q2TBS3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs454490723 | 3 | K>Q | No | EVA | |
| rs473124264 | 7 | H>P | No | EVA | |
| rs433681060 | 11 | I>F | No | EVA | |
| rs452144323 | 15 | D>E | No | EVA | |
| rs470625798 | 17 | P>R | No | EVA | |
| rs474935801 | 21 | Q>H | No | EVA | |
| rs462667474 | 21 | Q>P | No | EVA | |
| rs442806592 | 22 | F>I | No | EVA | |
| rs461345789 | 22 | F>L | No | EVA | |
| rs442806592 | 22 | F>V | No | EVA | |
| rs479911566 | 23 | K>E | No | EVA | |
| rs479911566 | 23 | K>Q | No | EVA | |
| rs459105925 | 24 | E>G | No | EVA | |
| rs477583713 | 25 | L>M | No | EVA | |
| rs451147729 | 25 | L>Q | No | EVA | |
| rs448024649 | 27 | P>A | No | EVA | |
| rs466529979 | 27 | P>R | No | EVA | |
| rs448024649 | 27 | P>S | No | EVA | |
| rs470537963 | 30 | E>G | No | EVA | |
| rs437732376 | 31 | P>T | No | EVA | |
| rs456221663 | 33 | V>A | No | EVA | |
| rs456221663 | 33 | V>G | No | EVA | |
| rs474914747 | 35 | H>Q | No | EVA | |
| rs454868212 | 43 | Q>H | No | EVA | |
| rs473407386 | 45 | V>G | No | EVA | |
| rs440472033 | 58 | V>G | No | EVA | |
| rs381887904 | 60 | S>G | No | EVA | |
| rs383422385 | 60 | S>N | No | EVA | |
| rs444637746 | 63 | V>G | No | EVA | |
| rs463123974 | 66 | V>G | No | EVA | |
| rs448705245 | 95 | T>P | No | EVA | |
| rs445633071 | 147 | E>G | No | EVA | |
| rs445145485 | 152 | D>Y | No | EVA |
No associated diseases with Q2TBS3
1 regional properties for Q2TBS3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SCP2 sterol-binding domain | 49 - 151 | IPR003033 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| sterol binding | Binding to a sterol, a steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| phospholipid transport | The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester. |
| positive regulation of intracellular cholesterol transport | Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells. |
| steroid biosynthetic process | The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9UJQ7 | SCP2D1 | SCP2 sterol-binding domain-containing protein 1 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MWKRIDHQLK | IKAGDGPQAG | QFKELGPGRE | PAVPHPLSLS | EFQTVPVFED | ISQHVKEVGS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QLVKKVNAIF | QLDITKDGKT | VHQWTIDLKN | GSGDTYRGPA | RLPADTVFTI | PEPVFMELIL |
| 130 | 140 | 150 | |||
| GKMNPQKAFL | AGKFKVSGKV | LLGQKLERVF | KDWAKW |