Q2S8Y9

PR
Gene name
tyrS
Protein name
Tyrosine--tRNA ligase
Names
Tyrosyl-tRNA synthetase, TyrRS
Species
Hahella chejuensis (strain KCTC 2396)
KEGG Pathway
hch:HCH_06238
EC number
6.1.1.1: Ligases forming aminoacyl-tRNA and related compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

54-127 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2S8Y9

Entry ID Method Resolution Chain Position Source
AF-Q2S8Y9-F1 Predicted AlphaFoldDB

No variants for Q2S8Y9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2S8Y9

No associated diseases with Q2S8Y9

4 regional properties for Q2S8Y9

Type Name Position InterPro Accession
domain GPS motif 799 - 852 IPR000203
domain CUB domain 41 - 149 IPR000859
domain GPCR, family 2-like, transmembrane domain 864 - 1118 IPR017981
conserved_site GPCR, family 2, secretin-like, conserved site 1106 - 1121 IPR017983

Functions

Description
EC Number 6.1.1.1 Ligases forming aminoacyl-tRNA and related compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
RNA binding Binding to an RNA molecule or a portion thereof.
tyrosine-tRNA ligase activity Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H(+).

1 GO annotations of biological process

Name Definition
tyrosyl-tRNA aminoacylation The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tyrosine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPSVEESLAL IKRGAEEIIQ EEGLIEKLKR GEPLRIKAGF DPTAPDLHLG HTVLINKLRQ
70 80 90 100 110 120
FQDLGHQVIF LIGDFTGMIG DPTGKSATRP PLTKEDVAQN AQTYKEQVFK ILDPKKTEVR
130 140 150 160 170 180
FNSEWMDKLS AADMIRLAGQ YTVARMLERD DFHKRYHGEQ SISIHEFLYP LVQGYDSVAL
190 200 210 220 230 240
RADVELGGTD QKFNLLMGRM LQKHYDQEPQ VIMTMPILEG LDGVQKMSKS LGNYIGVNDL
250 260 270 280 290 300
PGEMFGKLLS IPDELMWRYF ELLSFRDMAE IEDFKVQVNA GENPQNIKRL LAEEIVARFH
310 320 330 340 350 360
GGEAAQSAHK SAGNQVKLGE IPENVPVVHL EESDDQTEFS ISYILRRADL VKNGAAAKDV
370 380 390
LGRGAVFVDG AQVDPSFMVQ RGSEHVIQAG KKKIAQIFVK