Q2S1W0
Gene name |
hemE |
Protein name |
Uroporphyrinogen decarboxylase |
Names |
UPD, URO-D |
Species |
Salinibacter ruber (strain DSM 13855 / M31) |
KEGG Pathway |
sru:SRU_1702 |
EC number |
4.1.1.37: Carboxy-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2S1W0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2S1W0-F1 | Predicted | AlphaFoldDB |
No variants for Q2S1W0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2S1W0 | |||||
No associated diseases with Q2S1W0
4 regional properties for Q2S1W0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase | 171 - 306 | IPR006151 |
| domain | Glutamyl-tRNA reductase, N-terminal | 8 - 156 | IPR015895 |
| domain | Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain | 320 - 420 | IPR015896 |
| conserved_site | Glutamyl-tRNA reductase, conserved site | 99 - 122 | IPR018214 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.1.1.37 | Carboxy-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| uroporphyrinogen decarboxylase activity | Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protoporphyrinogen IX biosynthetic process | The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASFPSLDND | RLLRTARGEP | TDCTPVWMMR | QAGRYLPEYQ | AIRKEHSFFE | VVETPELAAE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VTIQPVERFS | LDAAILFCDI | MVVPEAMGLT | VKMVSGQGPT | FPKPLTTPDE | MERLVEPDVE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SALGHVFEAL | TVTRHELAGR | VPLIGFSGAP | WTLMAYMVEG | GGSKSYRAAR | RWLYRHPDAS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KALLQRTTDV | IVEYLIRQVD | AGAQMLQVFD | SWAGLHTPEN | FRTFCLPYLA | EIATRVKAAH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PDVPLVIFAK | GAHYALDALA | DTDYDVISLD | STMDPDAARD | TVGDRAVLQG | NLDPCALYAP |
| 310 | 320 | 330 | 340 | 350 | |
| PDVLRREVQH | MLAGFGPHHH | IGNLGHGMLP | DHDPEHARVF | VDAVHEHSRH | MRTV |