Q2RZH4

PR
Gene name
tdk
Protein name
Thymidine kinase
Names
Species
Salinibacter ruber (strain DSM 13855 / M31)
KEGG Pathway
sru:SRU_2559
EC number
2.7.1.21: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

28-101 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2RZH4

Entry ID Method Resolution Chain Position Source
AF-Q2RZH4-F1 Predicted AlphaFoldDB

No variants for Q2RZH4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2RZH4

No associated diseases with Q2RZH4

1 regional properties for Q2RZH4

Type Name Position InterPro Accession
conserved_site Thymidine kinase, conserved site 167 - 180 IPR020633

Functions

Description
EC Number 2.7.1.21 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
thymidine kinase activity Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate.
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
DNA biosynthetic process The biosynthetic process resulting in the formation of DNA.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDRDRTTGWM EVICGSMFSG KTEELIRRLR RARIARQHTR VFKPALDERY SEDEVVSHNE
70 80 90 100 110 120
NSVTTTPVEA PPQIQELVQE ADVVGIDEAQ FFDDDLVPTC QALAEDGHRV IVVGLDTDYR
130 140 150 160 170 180
AEPFDPMPQL MAVAEHVTKL HAVCVVCGAP ANHSQRIVPG EDRVLVGATE AYEPRCRACF
190 200 210 220
EPEPVTVTRP RPHTEALRAV ATDDADASTN EADPEAADAA SADGTAA