Q2RND2

PR
Gene name
tsaD
Protein name
tRNA N6-adenosine threonylcarbamoyltransferase
Names
N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Species
Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1)
KEGG Pathway
rru:Rru_A3569
EC number
2.3.1.234: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

158-266 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2RND2

Entry ID Method Resolution Chain Position Source
AF-Q2RND2-F1 Predicted AlphaFoldDB

No variants for Q2RND2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2RND2

No associated diseases with Q2RND2

2 regional properties for Q2RND2

Type Name Position InterPro Accession
domain Pseudouridine synthase, TruD, insertion domain 154 - 302 IPR011760
conserved_site Pseudouridine synthase TruD, conserved site 76 - 89 IPR020119

Functions

Description
EC Number 2.3.1.234 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
iron ion binding Binding to an iron (Fe) ion.
N(6)-L-threonylcarbamoyladenine synthase activity Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA.

1 GO annotations of biological process

Name Definition
tRNA threonylcarbamoyladenosine modification The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSMPFRVLGI ETSCDETAAA VVEPAADGRG GRIMAEALLS QVEEHRPYGG VVPEIAARSH
70 80 90 100 110 120
LDHVDSLVIR ALGEAGLTVH DIDAVAATGG PGLIGGVIVG VMTAKAIAQV AGKPFIAVNH
130 140 150 160 170 180
LEGHALTVRM TAGIDFPYLL LLASGGHCQL LAVEGVGRAK RLGTTIDDAA GEAFDKVAKM
190 200 210 220 230 240
LGLGYPGGPA VERAARRGDP RRFRLPRPLL DRPGCDLSFS GLKTAVRQTV EKLPPGPLSE
250 260 270 280 290 300
GDIADLCASF QAAVADCLAD RCRVAAGIFS ARHGRGRPLV VAGGVAANAS LRAALTEVAR
310 320 330 340 350 360
QADMTFVAPP LALCTDNAAM IAWVGVERLR LGLVDTMDFK PRPRWPLDPD APKAAGAGGV
KA