Q2RJM5

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Moorella thermoacetica (strain ATCC 39073 / JCM 9320)
KEGG Pathway
mta:Moth_1050
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-349 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2RJM5

Entry ID Method Resolution Chain Position Source
AF-Q2RJM5-F1 Predicted AlphaFoldDB

No variants for Q2RJM5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2RJM5

No associated diseases with Q2RJM5

6 regional properties for Q2RJM5

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 403 - 572 IPR000795
domain Small GTP-binding protein domain 405 - 562 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 52 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 329 - 377 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 678 - 793 IPR023115
domain Translation initiation factor IF-2, domain II 578 - 673 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKTRVYELA KELKVTNKDL IDTMARLGIY TRSHMSVLEN GEVIKVRNHY RQQWRAAKLA
70 80 90 100 110 120
RMHREQATLK GEGPVPTRGV PDAPRAEEVP SRQVPAPETG APAQATGATR QPATGSARPA
130 140 150 160 170 180
NTDETRVQEH KPATAARQAG DAPAAEGTAA AGQPLDGKEL RQAVANGQGT EEPRQQPAAT
190 200 210 220 230 240
GQRAQGGEAG RGQQSRQKKK RRGEGRSRQD ENKGSAREDQ ANRFATRDKE AAPSAGQQSP
250 260 270 280 290 300
AEKGQRRPAH SKPLRIPKPP EAVTKDLPEK RRDRSNARPG AKPAESGRSR KREMENQLEE
310 320 330 340 350 360
RLMRRDKNKG KAQKHKETPK VVFKITLTGS ITVQELAKRI GKTAAEVIKY LMGQGIMATI
370 380 390 400 410 420
NQELDLETAA LVAQDLGAIV EIKAEKPITE LEDLVDPPET LRERPPVVTV MGHVDHGKTS
430 440 450 460 470 480
LLDAIRRTNV TASEAGGITQ HIGAYQVRLK NRKITFLDTP GHAAFTAMRA RGAQATDIAI
490 500 510 520 530 540
LVVAADDGVM PQTIEAINHA KAAGVPIVVA INKIDRPEAN PERVKQQLTE YGLVPEEWGG
550 560 570 580 590 600
DTIMVPVSAV TKEGINDLLE MVLLTADVAE LKANPDRPAR GIVIEAKLDR GRGPVATMLV
610 620 630 640 650 660
QKGTLKIGDN LVAGSVYGRV RAMIDDRGER VNSAPPSTPV EVLGLSELPE AGDIFQVVED
670 680 690 700 710 720
EKLARQIASS RQEEKRQEEL KAASKTTLDD LFKQMEAGEV KELNLVIKGD VQGSVEALRG
730 740 750 760 770 780
ALEQLSTSEV KVNLLHGGVG AITETDVMLA AASKAIIIGF NVRPEANVRK AAEEAGVEIR
790 800 810 820 830 840
LYRVIYEVID DVKAAMSGLL EPEEREVILG RAEVRATFKV PKAGTVAGCF VTEGKIQNRA
850 860 870 880 890 900
LARVIRDGVV VFEGRIESLK RFKDDVREVA QGYECGVGLE KFNDIKEGDV IEAYTIEEIQ
REL