Q2RJH7

PR
Gene name
cobQ
Protein name
Cobyric acid synthase
Names
Species
Moorella thermoacetica (strain ATCC 39073 / JCM 9320)
KEGG Pathway
mta:Moth_1098
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

212-282 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2RJH7

Entry ID Method Resolution Chain Position Source
AF-Q2RJH7-F1 Predicted AlphaFoldDB

No variants for Q2RJH7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2RJH7

No associated diseases with Q2RJH7

3 regional properties for Q2RJH7

Type Name Position InterPro Accession
domain CobB/CobQ-like glutamine amidotransferase 255 - 451 IPR011698
domain Cobyric acid synthase, glutamine amidotransferase type 1 256 - 458 IPR033949
domain Cobyric acid synthase, N-terminal domain 3 - 226 IPR047045

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ABC-type vitamin B12 transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: vitamin B12(out) + ATP + H2O = ADP + an vitamin B12(in) + H+ + phosphate. Vitamin B12 is alkylcob(III)alamin.
catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

2 GO annotations of biological process

Name Definition
cobalamin biosynthetic process The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
glutamine metabolic process The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKAIMLQGT SSNVGKSVLA AALCRIFHRN GYRVSPFKSQ NMALNSGATP DGGEMGRAQI
70 80 90 100 110 120
VQAMAAGVVP RVEMNPILLK PTAHASSQVI VLGRPVGNLG AREYHGHFNQ KLWSRVEEAY
130 140 150 160 170 180
AFLEREFEII VIEGAGSPAE INLKAGEIAN MRVARMAGAP VLLVADIDRG GALAAVVGTL
190 200 210 220 230 240
ELLEPEERVM VAGIIINKFR GDLDLLKPAL DFLESRTGKP VLGVIPFLPD HGLPEEDSVV
250 260 270 280 290 300
LEGVTGRSTG AGEVEIAVIK LPCISNFTDF DALEREKGVN LRYVEAASDL GNPDLVILPG
310 320 330 340 350 360
SKNTIGDLLW LRCQGLETAI KELAGRGTPI IGICGGYQML GKEIRDPEHV ETDVEMIKGL
370 380 390 400 410 420
DLLPIKTVFQ TSKATNQVRG VVTGSGPFLG PLQGQEVQGY EIHMGASFLL DGRPAFKITS
430 440 450 460 470 480
RGGRLVTLDD GALAGEGRIW GTYIHGILDN DSLRHQVISV LRARRGLPAR PGMLNFMAEQ
490 500 510
ERRLDILAGE VARHLDLGRL AAIMGLERPL VWTGHDN