Q2NW23

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Sodalis glossinidius (strain morsitans)
KEGG Pathway
sgl:SG0377
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

97-325 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2NW23

Entry ID Method Resolution Chain Position Source
AF-Q2NW23-F1 Predicted AlphaFoldDB

No variants for Q2NW23

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2NW23

No associated diseases with Q2NW23

8 regional properties for Q2NW23

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 393 - 562 IPR000795
domain Translation elongation factor EFTu-like, domain 2 814 - 881 IPR004161
domain Small GTP-binding protein domain 396 - 552 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 316 - 366 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 57 - 95 IPR013575
domain Translation initiation factor IF- 2, domain 3 669 - 783 IPR023115
domain Translation initiation factor IF-2, domain II 569 - 662 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDVTVKSLA AEIQTPVDRL VQQFADAGID KTAVDSVTQQ EKETLLAHLN RDRGAAPNKL
70 80 90 100 110 120
TLQRKTRSTL NIPSTGGKSK SVQIEVRKKR TYVQRDPQAQ EQAEAEEQAR REAEELAQHQ
130 140 150 160 170 180
VQRDAEEKAK RAAEDKAKRE AAEQAKRVAA ESDKLTNQQT NTMTKSPQAT EKARREAEAA
190 200 210 220 230 240
ELRRKAEEET RRKVEEKARQ VAEEARRMAE ERGGNWDNAP EPAEEDTTDY HVNTSHHARE
250 260 270 280 290 300
AEDENDRKVE GDRRSRTRGG KATKQKKTSR LSESKADREE ARAVGRGGKG KRRPSTLTQG
310 320 330 340 350 360
FNKPAQAVNR DVVIGETITV AELANKMAVK GSQVIKAMMK LGAMATINQV IDQETAQLVA
370 380 390 400 410 420
EEMGHKVILR RENELEESVM SDRDTGSSAA AESRAPVVTI MGHVDHGKTS LLDYIRSTKV
430 440 450 460 470 480
AAGEAGGITQ HIGAYHVETD NGMITFLDTP GHAAFTAMRA RGAQATDIVV LVVAADDGVM
490 500 510 520 530 540
PQTIEAIQHA KAAKVPVVVA VNKIDKPEAD PDRVKNELTQ YGVIPEEWGG ESQFVHVSAK
550 560 570 580 590 600
SGAGIDELLD AILLQAEVLE LKAIRNGMAS GVVIESFLDK GRGPVATVLV REGTLNRGDI
610 620 630 640 650 660
VLCGFEYGRV RAMRDEVGRD VASAGPSIPV EILGLSGVPA AGDEATVVRD EKKAREVALY
670 680 690 700 710 720
RQGKFREVKL ARQQKSKLEN MFANMTEGEV SELNIVLKSD VQGSAEAISD ALEKLSNDEV
730 740 750 760 770 780
KVKIVGSGVG GITETDATLA AASNAILLGF NVRADASARR VIEAENLDLR YYSVIYDLID
790 800 810 820 830 840
EVKQAMSGML APEYKQEIIG LAEVRNVFRS PKFGAIAGCM VTEGVVKRHN KIRVLRENVV
850 860 870 880 890
IYEGELESLR RFKDDVNEVR NGMECGIGVK NYNDVRSGDV IEVFETIEIQ RTIA