Q2NU84
Gene name |
pncB |
Protein name |
Nicotinate phosphoribosyltransferase |
Names |
NAPRTase |
Species |
Sodalis glossinidius (strain morsitans) |
KEGG Pathway |
sgl:SG1016 |
EC number |
6.3.4.21: Other carbon--nitrogen ligases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2NU84
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2NU84-F1 | Predicted | AlphaFoldDB |
No variants for Q2NU84
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2NU84 | |||||
No associated diseases with Q2NU84
9 regional properties for Q2NU84
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Exoribonuclease, phosphorolytic domain 1 | 13 - 142 | IPR001247-1 |
| domain | Exoribonuclease, phosphorolytic domain 1 | 326 - 459 | IPR001247-2 |
| domain | S1 domain | 622 - 693 | IPR003029 |
| domain | K Homology domain | 555 - 620 | IPR004087 |
| domain | K Homology domain, type 1 | 560 - 616 | IPR004088 |
| domain | Exoribonuclease, phosphorolytic domain 2 | 145 - 208 | IPR015847-1 |
| domain | Exoribonuclease, phosphorolytic domain 2 | 462 - 532 | IPR015847-2 |
| domain | Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 239 - 323 | IPR015848 |
| domain | RNA-binding domain, S1 | 623 - 693 | IPR022967 |
Functions
| Description | ||
|---|---|---|
| EC Number | 6.3.4.21 | Other carbon--nitrogen ligases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| nicotinate phosphoribosyltransferase activity | Catalysis of the reaction: diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| NAD biosynthetic process | The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNVATDPILT | SILDTDAYKF | HMQQAVFHRY | HDVMVSAKFR | CRGYELLGEY | AADISAQVDM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MRGLQLNDDE | FTYLRGLPFF | QSDYLNCLRQ | FRFDPSQVRI | RNHHGKLDIR | ITGPWRDVIL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| WEVPLLAVIS | EVVHHRRSPQ | VTTADAVARL | RQKLLHFRRI | SEDLDTSRFR | LMDFGTRRRF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SRQVQFEVIA | ELQREFPYLI | GTSNYQLARE | RGLPPIGTQA | HEWFQAHQQI | SPDLANSQSA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ALQAWLDEYP | DRLGIALTDC | ITMDAFLRDF | GPSFARAYQG | MRHDSGDPVE | WGEKAIAHYQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QLGIDPLTKT | LVFSDSLDFD | KAFMLYRHFW | QRINLVFGIG | TRLTCDIPGI | KPLNIVIKLV |
| 370 | 380 | 390 | 400 | ||
| KCNGKPVAKL | SDSPGKIMCH | DKAFVRALRK | AFDVPLVVKK | AS |