Q2LQ86

PR
Gene name
rpoC
Protein name
DNA-directed RNA polymerase subunit beta'
Names
RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'
Species
Syntrophus aciditrophicus (strain SB)
KEGG Pathway
sat:SYN_00063
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

174-246 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2LQ86

Entry ID Method Resolution Chain Position Source
AF-Q2LQ86-F1 Predicted AlphaFoldDB

No variants for Q2LQ86

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2LQ86

No associated diseases with Q2LQ86

6 regional properties for Q2LQ86

Type Name Position InterPro Accession
domain RNA polymerase, alpha subunit 345 - 486 IPR000722
domain RNA polymerase, N-terminal 236 - 515 IPR006592
domain RNA polymerase Rpb1, domain 3 490 - 630 IPR007066
domain RNA polymerase Rpb1, domain 1 16 - 343 IPR007080
domain RNA polymerase Rpb1, domain 5 753 - 1296 IPR007081
domain RNA polymerase Rpb1, domain 4 661 - 750 IPR007083

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

4 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
magnesium ion binding Binding to a magnesium (Mg) ion.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEDVFSYFEK PKDPIRFNAI KISIASPDKI LSWSYGEVKK PETINYRTFK PERDGLFCAK
70 80 90 100 110 120
IFGPVKDYEC LCGRYKRMKH RGVVCEKCGV EVIKSKVRRE RMGHITLATP VAHIWFLKSL
130 140 150 160 170 180
PSRIGNVLDL TLKELERILY FESWIVLDPR NTPLRKKDLL SDEEYNDLRE QYGPDGFQAG
190 200 210 220 230 240
IGAEAVRKLL EEVDLEGLDV ELRDELKTAS SDTKRKKVIK RLKVIEALRK SGNRPEWMIL
250 260 270 280 290 300
TVLPVIPPDL RPLVPLDGGR FATSDLNDLY RRVINRNNRL KRLQELNAPE IIIRNEKRML
310 320 330 340 350 360
QEAVDVLFDN GRRGRAITGT NKRPLKSLSD MLKGKQGRFR QNLLGKRVDY SGRSVITVGP
370 380 390 400 410 420
DLRLHQCGLP KKMALELFKP FVYNRLQEKG YVTTVKSAKK MVERETAEVW DALDEVVREY
430 440 450 460 470 480
PVMLNRAPTL HRLGLQAFEP VLIEGKAIQL HPLVCTAFNA DFDGDQMAVH VPLSIEAQTE
490 500 510 520 530 540
ARVLMMSTNN ILSPANGKPI IIPSQDVVLG IYYLTRSKED VLGHGMSFSN PEEVRSAFDA
550 560 570 580 590 600
GAVELRARIK VRIDDELKET TVGRVILYEI IPEAISFDVI NKVMNKKELA NLIDYCYRLC
610 620 630 640 650 660
GEKTTVILAD RLKDMGFKYA THSGMSFAVR NLNIPKNKKD IVVRADRDVL EIQKQYMDGL
670 680 690 700 710 720
ITDGERYNKV IDLWAQATEK IASEMMGGIE TEEQITTEGK KVVESFNPIY MMADSGARGS
730 740 750 760 770 780
NAQIRQLAGM RGLMAKPSGE IIETPITANF REGLTVLQYF ISTHGARKGL ADTALKTANS
790 800 810 820 830 840
GYLTRRLVDV AQDCIITQQD CGTVDGISVS ALMEGGEIIE TAGERVLGRV VLEDIMDPFT
850 860 870 880 890 900
GEVLVGANQE IDESLSEKID RAGIESVRIR SVLTCKAKYG VCARCYGRDL GHGHLVNIGE
910 920 930 940 950 960
AVGIIAAQSI GEPGTQLTMR TFHIGGTAKF EEHSTLDSRH DGIVKYVDLN YVVSKIGETV
970 980 990 1000 1010 1020
VMSRHGEIHV LDEQLRSRGK YTVPYGAHLK VKDGQSVKRG DRMAEWDPFS IPILAEVDGT
1030 1040 1050 1060 1070 1080
VKFGDIIEGK TMQEQVDEVT GLSRKVIVEF KGADLRPRVS LKDATGKTAK VPGTNAAARH
1090 1100 1110 1120 1130 1140
LLSVGVNIVV SEGDQVKAGD IIAKIPRETT KTKDITGGLP RVAELFEARK PKDFAVISEI
1150 1160 1170 1180 1190 1200
DGVVSYGKDA KGKRKVIVTP EIGDEKEYLI PKGKHVSVQE GDRVIAGEAL MSGVNNPHDL
1210 1220 1230 1240 1250 1260
LMIKGEKALA RYLVDEVQEV YRLQGVKIND KHMEVIVRQM LRRVKVIDPG DTPFMADEQV
1270 1280 1290 1300 1310 1320
EKFRFQEENE KAIARGEQPA IGEPVLLGIT KASLSTQSFI SAASFQETTR VLTEASLAGK
1330 1340 1350 1360 1370 1380
VDYLRGLKEN VIMGRLIPAG TGLVMYRKLG IKTVADEDAE SVEIEGDENS NKKSLDMHAA
N